In Spider-Man, who is Spider-Man's archenemy?

Answer 1

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If there is just one, it's Green Goblin.  But I think I would argue that none of SM's rogue's gallery really stands head and shoulders above the rest.  Like GG is the guy, but he's not like Joker or Lex Luthor where he's the quintessential Spider-Man villain.

Answer 2

The green goblin.