Why don't eukaryotic small ribosomal subunits stay on the mRNA like in polycistronic mRNA?
In polycistronic mRNA in prokaryotes, after translating and terminating one protein the small ribosomal subunit remains on the mRNA and continues scanning for the next starting place. But in eukaryotes, once a stop codon is reached the polypeptide is terminated and the ribosome falls apart and off the mRNA. Why doesn't it remain on the strand? What is it about the release factor that causes the ribosome to fall off?
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