My brother has been doing drugs at a young age like 18 years old; how long would it take for him to have health problems?

He is now 21 years and he is doing drugs every night and does it all the time in college. He does all the drugs and smokes regular cigarettes. He mixes his drugs and he will do one different drug a night and another drug another day. If he smokes that many times a day how long would it take for him to have health... show more He is now 21 years and he is doing drugs every night and does it all the time in college. He does all the drugs and smokes regular cigarettes. He mixes his drugs and he will do one different drug a night and another drug another day. If he smokes that many times a day how long would it take for him to have health problems or cancer?
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