Well, I did, but I recognized that to get anywhere, I'd need a graduate degree -- a PhD, which I did earn. My graduate studies were funded by a fellowship; I didn't need more loans, and I hadn't had large loans as an undergraduate, because I attended the sort of college that has a lot of financial aid to offer.
If you are interested in a humanities field and are passionate enough about it that you think you'd like to work in it as a serious scholar, do what I did.
If it's something like studio art, creative writing, or drama -- you need to decide just how passionate you really are. I know some successful artists, novelists, and actors, but they experienced some long lean years before they became successful, and many other people in the arts never achieve any success.
But if you have to cripple yourself with loans, don't do it. You won't be able to repay large loans while waitressing in the hope of getting your big break as an actress or something.