Can a business relocate?

I am living in my deceased mom's home at the time. I am not sure I can afford it. I have a brother that lives 5 hours away. If I ask him if he has an interest in buying the house he will not answer me. He has a business of his own for 17 years that earns him money from highway billboards. Could my brother move... show more I am living in my deceased mom's home at the time. I am not sure I can afford it. I have a brother that lives 5 hours away. If I ask him if he has an interest in buying the house he will not answer me. He has a business of his own for 17 years that earns him money from highway billboards. Could my brother move 5 hours away from where he grew his business or is it unlikely?
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