If you only have 8 GB of RAM (as you stated in a different comment), setting up a RAM drive and running a game from it may actually be counterproductive, as with 8 GB, just the OS will already starting to swap heavily. Swapping the RAM drive is definitely something you want to avoid.
In any case, running a game from RAM or SSD will usually only improve the screen load times (depending on the game, when you e.g. switch from one location to another), not the actual game performance. That is mostly governed by the GPU, the CPU and the available physical RAM (more or less in that order). Since you're runnig form an (otherwise unspecified) laptop, my guess is that the GPU is the bottleneck in your case.
Post the detailed laptop specs and the game you're talking about, and maybe someone could give you a better answer.