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The reaction "cascade" in glycolysis can't contribute without unloading --- from NADH?

Hydrogen, oxygen, or nitrogen.

1 Answer

  • Ted K
    Lv 7
    3 years ago
    Favorite Answer


    A key reaction in glycolysis is the conversion of glyceraldehyde 3-phosphate (G3P) to 1,3, diphosphoglycerate, catalyzed by the enzyme, G3P dehydrogenase, which requires NAD+ (i.e. the oxidized pyridine nucleotide) as a cofactor. Under aerobic conditions, NADH --> NAD+ by giving up its H+ to the electron transport chain. Under anaerobic conditions the NAD+ is regenerated by reducing pyruvate to lactate.

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