What will occus if a drug at the neuromuscular junction blocks the receptor sites on the postsynaptic membrane?

A) Inhibition of acetylcholine release

B) Muscular contraction

C) Muscle paralysis

D) Release of calcium ions

2 Answers

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  • 3 years ago
    Best Answer

    C

    "Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction,[1] causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically via the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors of the motor nerve end-plate. While some drugs act presynaptically (such as botulinum toxin and tetanus toxin), those of current clinical importance work postsynaptically."

    https://en.wikipedia.org/wiki/Neuromuscular-blocki...

    • Ahmed Khan3 years agoReport

      Why didn't you go for option A) as Muscle Paralysis would be caused by following mechanism?
      "This is accomplished either by acting presynaptically via the inhibition of acetylcholine (ACh) synthesis"

  • 3 years ago

    C) Muscle paralysis - no transmission of the impulse to the muscle.

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