What will occus if a drug at the neuromuscular junction blocks the receptor sites on the postsynaptic membrane?
A) Inhibition of acetylcholine release
B) Muscular contraction
C) Muscle paralysis
D) Release of calcium ions
- bravozuluLv 74 years agoFavorite Answer
"Neuromuscular-blocking drugs block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. This is accomplished either by acting presynaptically via the inhibition of acetylcholine (ACh) synthesis or release or by acting postsynaptically at the acetylcholine receptors of the motor nerve end-plate. While some drugs act presynaptically (such as botulinum toxin and tetanus toxin), those of current clinical importance work postsynaptically."
- Formerly Peter SLv 74 years ago
C) Muscle paralysis - no transmission of the impulse to the muscle.