380, 25 acp, 22LR/22Magnum for Home Defense?

Are those Heritage revolvers or Cobra guns that I see on many places online (and still in stock and that are around $200) good for home defense such as a HER 22LR/22Magnum revolver, a .380 Cobra or a 25 acp? What about under $250 Russian, Polish or Czech guns? I've seen videos of them on youtube, I... show more Are those Heritage revolvers or Cobra guns that I see on many
places online (and still in stock and that are around $200) good for
home defense such as a HER 22LR/22Magnum revolver, a .380 Cobra
or a 25 acp? What about under $250 Russian, Polish or Czech guns?

I've seen videos of them on youtube, I can't really tell if they are weak,
pea shooters or powerful, what if I use 22 Magnum ammo, can that be
used for home defense? What type would you use?

Also: Can .380, 25acp, 22LR and 22 Magnum kill?

At the target range (I've shot 9mm and other types of guns before, a few times) I'm somewhat good at center of mass shots to the chest area and somewhat better at head shots, but if I use these calibers for protection I don't want any animal or human to bleed to death if used for hunting back up or defense, will they kill instantly via a shot to the head or heart, regardless of animal or human?

Thanks.
3 answers 3