What do plasma b-cells do?
Can someone explain this in English? Not in scienceese, thanks
- JoeLv 47 years agoFavorite Answer
As "non-scienceese" as I can...
So plasma cells can do a couple of things... But first, it might be helpful to know what plasma cells are and how they come about being "plasma" B cells
So, they start off as "naive" B cells or immature B cells with minimal responsibilities...
Along comes an activated T-Helper cell with a set of specific receptors and an Antigen... the antigen is some foreign object(or it can be a persons specific protein in the case of autoimmune disease)...
So these T- cells "bump" into naive B cells... as they bump into one another the T helper cell transfers the antigen onto the B cell...transforming it into a "Plasma B- Cell"
Once these plasma B cells form, they provide 2 important functions:
1.They can produce antibodies
2.They can become memory cells
- 1.Plasma B cells are like sophisticated 3D printing xerox machines... they have special genes and proteins that allow them to copy any foreign material transferred to them (most of the time its some protein that doesnt belong in your body). So they scan the foreign material, and print a specific "antibody" that matches the antigen. Once these antibodies are built, they can be released into your blood or lymphatic system or tissues in order to help defend your body. This would be considered as the initial (primary) step.
- 2. As a secondary step, the Plasma B cell can become (and make) memory B cells. Why? So that if this same foreign material gets into your system, it doesnt have to be delayed by going down this route. (T cells to B cell activation). Plasma B cells, can copy the antigen and "store as memory" of what this antigen was built like. Then, if this same antigen presents itself, the memory B cells can self replicate (via mitosis) and amplify the amount of antibodies necessary to fight off infection in short period of time. Memory cells dont actually produce antibodies, but rather have antibodies on their surface. (on stand by)
It is important to note that plasma B cells do not directly kill the foreign product. They simply tag the foreign material with antibodies. These tags release various "SOS" calls (called cytokines) to other cells and systems. Example: If a bacteria were to infect a person, antibodies would attach to it, clump it up so that it becomes inactive and then these antibodies would signal a set of proteins called complement proteins. This complement complex comes and recognizes the foreign material because of the antibodies and destroys the bacterial cell membrane.
Kind of long... Hope it helps
- Anonymous7 years ago
You have several types of white blood cells. One type is the lymphocyte. There are two main types of lymphocyte: B lymphocytes and T lymphocytes. B lymphocytes are also called B cells. When a B cell "recognises" an antigen (which stimulates an immune response) the B cell rapidly produces thousands of cloned (genetically identical) cells called plasma cells. The plasma cells then synthesise and secrete antibodies. The antibodies attach to whatever has the antigen. Antibodies have different functions. They may stick cells together. They may mark cells for destruction.
- Ted KLv 77 years ago
So-called plasma cells are a type of B lymphocyte (aka "B cells") that are specialized for producing and secreting antibodies.