Herpes zoster blood test?

What do the two particular antibodies IgG and IgM indicate if a person is being tested for a herpes zoster infection? Will both of them come out positive which will confirm an infection or just one being positive will be enough?

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  • 6 years ago
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    IgM antibody in blood; this appears only during chickenpox or herpes zoster and not while the virus is dormant.

    A positive IgG result coupled with a positive IgM result suggests recent infection with varicella-zoster virus (VZV). This result should not be used alone to diagnose VZV infection and should be interpreted in the context of clinical presentation.

    A positive IgG result coupled with a negative IgM result indicates previous vaccination to or infection with VZV. These individuals are considered to have protective immunity to reinfection.

    A negative IgG result coupled with a negative IgM result indicates the absence of prior exposure to VZV and nonimmunity. However, a negative result does not rule out a VZV infection. The specimen may have been drawn before the appearance of detectable antibodies. Negative results in suspected early VZV infections should be followed by testing a new serum specimen in 2 to 3 weeks.

    Equivocal results should be followed up with testing of a new serum specimen within 10 to 14 days.

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