我要做research about liver transplant for liver failure, can you help me to answer the question(you can search in the internet) you can copy but the information must related to the qusetion.)
1Liver transplant invented to treat the same disease as the one it is still treating today?
2Is it possible to use Liver transplant for other diseases?(除左用來醫 liver failure )
3Is this liver transplant effective in treating the disease compared to other treatment methods?
4.What are the benefits and limitations of using liver transplant to treat the specific disease?
pin****** ( 初學者 5 級 ) please no wiki!!!
- 7 years agoFavorite Answer
The first human liver transplant was performed in 1963 by a surgical team led by Dr. Thomas Starzl of Denver, Colorado, United States. Dr. Starzl performed several additional transplants over the next few years before the first short-term success was achieved in 1967 with the first one-year survival post transplantation. Despite the development of viable surgical techniques, liver transplantation remained experimental through the 1970s, with one year patient survival in the vicinity of 25%. The introduction of cyclosporin by Sir Roy Calne markedly improved patient outcomes, and the 1980s saw recognition of liver transplantation as a standard clinical treatment for both adult and pediatric patients with appropriate indications. Liver transplantation is now performed at over one hundred centers in the US, as well as numerous centres in Europe and elsewhere. One-year patient survival is 80–85%, and outcomes continue to improve, although liver transplantation remains a formidable procedure with frequent complications. The supply of liver allografts from non-living donors is far short of the number of potential recipients, a reality that has spurred the development of living donor liver transplantation. The first altruistic living liver donation in Britain was performed in December 2012 in St James University Hospital Leeds.
Prognosis is quite good, but those with certain illnesses may differ.There is no exact model to predict survival rates; those with transplant have a 58% chance of surviving 15 years. Failure of the new liver occurs in 10% to 15% of all cases. These percentages are contributed to by many complications. Early graft failure is probably due to preexisting disease of the donated organ. Others include technical flaws during surgery such as revascularization that may lead to a nonfunctioning graft.
2013-11-05 21:30:03 補充：
you will find more on : http://en.wikipedia.org/wiki/Liver_transplantationSource(s): website, http://en.wikipedia.org/wiki/Liver_transplantation