If HeLa cells came from Henrietta Lacks, where did colon cancer cell line (HCT116) originate?
The Internet gives very poor information about colon cance cell line (HCT116) :(
- JLILv 76 years agoBest Answer
I don't think we will ever know. HCT do not represent the patients initials. I am guessing, that H= Human, C= Colon and T= tumour, and 116 refers to nr. 116 in a database. Here is the paper that describes how it was made: http://cancerres.aacrjournals.org/content/41/5/175... And here is a datasheet where we additionally are told, that the patient was a male: http://ezbiosystems.com/view2.asp?d_id=160
Concern about patient anonymity wasn't an issue back in the 1950´s
- RAY GLv 76 years ago
Even papers in Google Scholar don't contain this information.
All that's findable is that it was from epithelial tissue of an adult male with colorectal carcinoma, and the commercial specification sheet says the same: http://www.lgcstandards-atcc.org/Products/All/CCL-...