m89065 asked in 社會與文化語言 · 7 years ago

英文文獻翻譯!!急急急~贈15點

Purpose: Malnutrition and chronic inflammation in dialysis patients negatively impacts prognosis. However, intervening to correct this problem (through nutritional supplementation) is often hampered by poor compliance due to both medical and socioeconomic barriers. We have therefore performed a pilot study to investigate the technical feasibility of “directly observed treatment” of nutritional supplementation (protein and omega-3 fatty acids), administered during regular dialysis sessions. Secondary end points included observation of nutritional and inflammatory status of hypoalbuminemic patients undergoing hemodialysis.

Methods: Main inclusion criteria were serum albumin # 3.9 g/dL (3 months prior to the study).Sixty-three eligible patients agreed to participate. Two intervention groups received 30 mL of a liquid protein supplement plus either 2.4 g omega-3 (1800 mg eicosapentaenoic acid + 600 mg docosahexaenoic acid) or a placebo, three times per week after their routine dialysis session for 6 months. Serum albumin, plasma lipids, and other indicators of nutritional and inflammatory status were measured.

Results: Directly observed nutritional supplementation resulted in a significant improvement in the low density lipoprotein cholesterol/high density lipoprotein cholesterol ratio in the omega-3 group as compared to the placebo group (P = 0.043). For the omega-3 group, serum albumin was also marginally higher after 6 months as compared to baseline (P = 0.07). The observed increase in C-reactive protein in the placebo group over 6 months was not apparent in the omega-3 group, although there was no significant difference between groups. Nuclear factor kappa B, malnutrition-inflammation score, normalized protein nitrogen appearance, body mass index, and hemoglobin were unaffected by the intervention.

Update:

可以不要google或奇摩翻譯,希望能修飾過句子!! 謝謝!

2 Answers

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  • 7 years ago
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    目的:透析患者營養不良和慢性炎症負面影響預後。然而,往往是阻礙干預來修正這個問題(通過營養補充品)的依從性差,由於醫療和社會經濟障礙。因此,我們進行了試驗研究,以探討“直接觀察治療”補充營養(蛋白質和ω-3脂肪酸),在常規透析會話管理的技術可行性。次要終點包括低白蛋白血症的血液透析患者的營養和炎症狀態的觀察。

    方法:主要入選標準為血清白蛋白#3.9克/升(前3個月的研究),62個符合條件的患者同意參加。兩個干預組收到了30毫升的液體補充蛋白質加中要么2.4克的ω-3(1800毫克二十碳五烯酸600毫克二十二碳六烯酸)或安慰劑,一周後他們的日常透析三次,每次6個月。血清白蛋白,血脂,營養和炎症狀態等指標進行了測量。

    結果:直接觀察到的營養補充,導致在一個顯著的改善,低密度脂蛋白膽固醇/高密度脂蛋白膽固醇的比例ω-3組較安慰劑組(P=0.043)。對於ω-3組中,血清白蛋白也略高基線(P=0.07)相比,6個月後。超過6個月,而安慰劑組的C-反應蛋白明顯上升並不明顯的ω-3組,組之間雖然沒有顯著的差異。核因子kappa B,營養不良炎症評分,外觀正常的蛋白質氮,身體質量指數和血紅蛋白不受干預。

    Source(s): Googel
  • Anonymous
    7 years ago

    我每次都是去這里看的哦, http://Lvmiss。com

    厎借勄

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