Ach and Stroke Volume?
Why can acetylcholine cause an increase in stroke volume?
- Anonymous7 years agoFavorite Answer
Not acetylcholine - see below:
An Increase in Sympathetic Activity Increases Stroke Volume
The cardiac muscle cells of the ventricular myocardium are richly enervated by sympathetic nerve fibers. Release of norepinephrine by these fibers causes an increase in the strength of myocardiall contraction, thus increasing stroke volume. Norepinephrine is thought to increase the intracellular concentration of calcium in myocardial cells, thus facilitating faster actin/myosin cross bridging. Also, a general sympathetic response by the body will induce the release of epinephrine from the adrenal medulla. Epinephrine, like norepinephrine will stimulate an increase in the strength of myocardial contraction and thus increase stroke volume.
- JanosLv 57 years ago
Just like the person above said, the increased SV (stroke volume) is increased my the hearts contractions due to the catecholamines hormones. ACh is a neurotransmitter, it can lower the heart rate.Source(s): Physiology of Sport and Exercise