Amitriptyline is used to treat symptoms of depression. Amitriptyline is in a class of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. Amitriptyline is also used to treat eating disorders, post-herpetic neuralgia (the burning, stabbing pains, or aches that may last for months or years after a shingles infection), and to prevent migraine headaches.
It has got many adverse effects (hypertensive effects, cardiac conduction, heart rate and proarrhythmic effects).
Sertraline is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks), posttraumatic stress disorder (disturbing psychological symptoms that develop after a frightening experience), and social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life). It is also used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. Sertraline is in a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.
The most effective psychosocial treatment for depression in patients with myocardial infarction is cognitive-behavior therapy. Efficacy and adverse effects are important considerations when selecting a pharmacologic agent for treatment of depression following myocardial infarction. During the past two decades, selective serotonin reuptake inhibitors (SSRIs) have emerged as first-line agents in the treatment of mild to moderate depression.
Answer: D) Referral for intense interpersonal psychotherapy. If it fails, (B) Sertraline (Zoloft) may be considered.
Please note that I am not a medical professional.