Supa asked in HealthOther - Health · 9 years ago

Is ketamine a safe recreational drug?

So I read from two sources, and they more or less disagree with each other.

This is taken from wiki

"The first large-scale, longitudinal study of ketamine users found that heavy ketamine users had impaired memory by several measures, including verbal, short-term memory and visual memory. However, occasional (1-2 times per month) ketamine users and former ketamine users were not found to differ from controls in memory, attention and psychological well-being tests. This suggests that occasional use of ketamine does not lead to prolonged harm and that any damage that might occur may be reversible when ketamine use is stopped; however, depression worsened even in the abstinent user group over the period of the study (one year), along with dissociative symptoms still existing among infrequent users.[33]

Short-term exposure of cultures of GABAergic neurons to ketamine at high concentrations led to a significant loss of differentiated cells in one study, and non-cell-death-inducing concentrations of ketamine (10 μg/mL) may still initiate long-term alterations of dendritic arbor in differentiated neurons. The same study also demonstrated that chronic (>24 h) administration of ketamine at concentrations as low as 0.01 μg/mL can interfere with the maintenance of dendritic arbor architecture. These results raise the possibility that chronic exposure to low, subanesthetic concentrations of ketamine, while not affecting cell survival, could still impair neuronal morphology and thus might lead to dysfunctions of neural networks.[34][35]"

and now-

"He and his team found that the drug not only improved the rats' depression-like behaviors, it also restored connections between neurons or brain cells that had been damaged by chronic stress. They called this "synaptogenesis"."

I have never taken a biology course before... Can someone please share their understanding?

2 Answers

  • Anonymous
    9 years ago
    Favorite Answer

    I'm from Rotterdam, The Netherlands.

    We like to party hard here. So XTC, Speed, Ketamine etc are always available here at our clubs.

    But let's just keep things simple: Ketamine fcks you up. Don't use it.

    That simple.

  • 9 years ago

    there is no such thing as a safe recreational drug. a drug by nature alters either mental, emotional, or physical states that affects the body/mind. doing so without medical reason is always a bad idea.

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