What is wrong?! Enlarged liver and spleen.?
A month ago I went to the ER because I have horrible lower abdominal pain, they did a CT Scan and found that unrelated to my pain I have an enlarged liver and spleen. I have been seeing a doctor who has ran blood test after blood test and she can't figure out what is wrong. She referred me to someone else to see if he can diagnose me. What's showed in my blood work is my thyroid hormone is slightly elevated, low estrogen, and high iron.
- aWellWisherLv 78 years agoFavorite Answer
Some allergy, chronic infection, parasitic infestations are some of the common causes. Sometimes it is idiopathic, that is, the cause is unknown. In your blood work, high iron is significant. It may be causing hemosiderosis or secondary hemochromatosis. See here-
Also, all these things need to be corroborated with your symptoms and signs on physical examination. Hope it helps. All the best!
- abijannLv 78 years ago
There are many different causes of liver cell damage...
read this and see if any may pertain to you:
1. Alcohol consumption: overconsuming alcohol in
a short time period, consuming alcohol over long
time periods, or taking alcohol with medications.
2. Chemical exposure: chemical like carbon
3. Medication toxification: some drugs are harder
on the liver than others are and some can become
toxic....it depends on a person's sensitivity to them.
4. Mushroom poisoning
5. Hereditary conditions: such as Hemochromatosis...
where the body holds onto too much iron; Wilson
disease...where the body holds onto too much copper.
These tend to build up inside of organs
6. Metabolic disorders: such as the liver lacking
an enzymes, thyroid problems, liver not handling
glucose well, etc
7. Viral infections...like Hepatitis A,B,C
8. Parasite infections: liver fluke
9. Cardiac/vascular problems
10. Auto immune disease: like biliary cirrhosis or
11. fatty liver disease: which could be weight related;
cholesterol/triglycerides high, diabetes, alcohol, or
13. biliary obstruction/malformation/infections
and there are others.
Some people may have an enlarged spleen and
liver because of Mononucleosis...which in time can
You should be seeing a specialist...either a
gastroenterologist or hepatologist.
The liver doesn't normally cause pain, unless it
has enlarged in size due to inflammation developing
in it...then it can become like a dull ache to a feeling
of fullness in the area. That is located in the upper
right hand quadrant of the abdomen, up under the
front rib cage. Pain there can also be associated
with gallbladder/biliary problems. Pain in the lower
right part of the abdominal area can be
In liver disease, where the cells become damaged,
the immune system of the body responds to this
and causes inflammation to develop inside the liver...
this will cause the liver to enlarge in size. Because
the blood that normally flow through the liver is
hampered...it can also cause the spleen to
enlarge, because the blood backs up into it.
The portal vein is the main vein where all the blood
to from the entire abdominal area flows through
to the liver, before it returns to the heart.
If it cannot flow through the liver well, it backs
up at times into smaller vessels not used to
handling this amount of blood and they can have
weak spots and easily break open. If this should
occur (any blood in the sputum, vomit, or rectal
area) it needs checked out immediately (emergency)...
the doctors can go in a band the vessels to stop the
Best wishesSource(s): caregiver to a liver transplant patient