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How many subunits does an ionotropic ACh receptor have?

How many subunits does an ionotropic ACh receptor have and which transmembrane domain of each subunit lines the ion channel pore?

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  • 8 years ago
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    Bios 240? ;)

    According to the book: Ionotropic receptors have 5 subunits which surround a central ion channel. Each subunit has a similar structure, with 4 membrane-spanning segments. (M1-M4). The M2 segment lines the pore.

    Source(s): Animal Physiology - Hill, Wyse, Anderson. Chp. 12, Table 12.3 and Figure 12.16.
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