Anonymous asked in 社會與文化語言 · 8 years ago


SUBJECTS AND METHODSStudy populationThe Blue Mountains Eye Study is a population-based cohort study of vision, common eye diseases, and other health outcomes in an urban, predominantly white population aged _49 y. The 1992–1994 baseline study examined 3654 eligible residents of 2 postal codes of the Blue Mountains region, west of Sydney,Australia (82.4% response). Participants were reexamined every5 y: 2335 (75.1% of survivors) at the second examination in 1997–1999, and 1952 (76.5% of survivors) at the third in 2002–2004. The study was conducted in accordance with recommendations of the Helsinki Declaration and was approved by the University of Sydney and Sydney West Area Health Service Human Research Ethics Committees. Written informed consentwas obtained from all participants.Mortality from inflammatory diseases Mortality data since baseline (13 y) were obtained via data linkage with the Australian National Death Index (NDI) in December 2005. Information provided by family members during follow-up was also included for participants whose death was reported before 31 December 2005. The major underlying cause of death recorded by the NDI was used to identify inflammatory disease–related causes of deaths. For comparative purposes, CVD mortality was also determined. The sensitivity and specificity of Australian NDI data were estimated to be 93.7% and 100% for all-cause deaths, respectively, and 92.5% and 89.6%, respectively, for CVD mortality (13).As proposed by Jacobs et al (12), non-CVD, noncancer inflammatory diseases that had an inflammatory, oxidative stress, or infectious component as the predominant pathophysiology were considered inflammatory diseases. We followed their scheme and examined each International Classification of Disease (ICD) code that occurred in our sample. The causes of death (by disease groups) that we considered to be related to inflammatory diseases are shown in Table 1.

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  • 阿昌
    Lv 7
    8 years ago
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    藍山眼科研究是基於人群的隊列研究的視野,常見的眼科疾病,和其他城市,以白色為主年齡_49的人口健康成果。 1992-1994年基線研究36542,悉尼以西的藍山地區,澳大利亞(82.4%響應)郵政編碼資格的居民。與會者們重新審視每

    5 :2335生還者(75.1%),在1997-1999年的第二次考試,1952年在2002-2004年的三分之一(76.5%)的倖存者。這項研究是在按照“赫爾辛基宣言”的建議,是由大學,悉尼和悉尼西部地區健康服務人類研究倫理委員會批准。知情同意書



    自基線的死亡率數據(13年)獲得通過數據連接與澳大利亞國立死亡指數2005年12月。隨訪期間,由家庭成員提供的信息還包括其死亡2005年12月31日之前報告的參與者。 記錄的主要死亡的根本原因被用來確定炎性疾病相關的死亡原因。為便於比較,心血管疾病死亡率也決心。估計為93.7%和100%,所有原因死亡,分別,分別為92.5%和89.6%,心血管疾病的死亡率(13),澳大利亞數據的敏感性和特異性。


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