總膽固醇與腫瘤的關係

麻煩請專業人士告訴我

我找到報告內乳癌病患會有鈣與總膽固醇上升的情況

目前我知道血鈣會上升是因為腫瘤細胞分泌副甲狀腺類蛋白造成高鈣血症。

但是總膽固醇為什麼也會上升呢??

找了很多本書都是說膽固醇上升的後果

或是有可能是因為脂肪攝取過多什麼的....

但都不是我要的,因為其他脂肪含量和膽固醇都是正常的!!

我只想要知道為什麼乳癌會造成總膽固醇上升?

跟用藥或是什麼腫瘤分泌了激素有關嗎??

麻煩請替我解惑謝謝。

2 Answers

Rating
  • 8 years ago
    Best Answer

    這一篇認為飲食/膽固醇/乳癌之間未發現因果關聯性

    給您參考

    Breast Cancer Res Treat. 2011 Jan;125(1):181-9. Epub 2010 May 13.Associations between mammographic density and serum and dietary cholesterol.AbstractAlthough high mammographic density is a risk factor for postmenopausal breast cancer, its etiology remains unclear. We examined whether serum and dietary cholesterol, which increase breast cancer risk and are involved in endogenous estrogen formation, were associated with increased mammographic density. We conducted a cross-sectional analysis of 302 healthy, sedentary postmenopausal women, aged 50-74 years, enrolled in the Alberta Physical Activity and Breast Cancer Prevention Trial between 2003 and 2006. In multiple linear regression models, no significant associations were observed between serum lipids and percent density or dense tissue area (Percent density: b (change in square root percent density per unit change in cholesterol level) = -0.06 (95%CI = -0.26 to 0.13); b = 0.06 (95%CI = -0.48 to 0.61); and b = -0.11 (95%CI = -0.33 to 0.10) for total cholesterol, high-, and low-density lipoprotein, respectively; similar results found for dense area). Alcohol consumption modified the association between triglycerides and percent density (>1 drink/day: b = -0.94 (95%CI = -1.79 to -0.10); ≤ 1 drink/day: b = 0.19 (95%CI = -0.12 to 0.50); and no alcohol consumption: b = 0.15 (95%CI = -0.44 to 0.73).We found no evidence indicating any association between dietary and serum cholesterol levels and mammographic density.

  • 8 years ago

    這方面的問題你可以跟我聯繫我找專人為你解決

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