Anonymous asked in Science & MathematicsMedicine · 9 years ago

what is "sodium sieving"?

it has to do with peritoneal dialysis but ive got no clue what it is!!!

1 Answer

  • Anonymous
    9 years ago
    Favorite Answer

    Sodium sieving is a consequence of dissociation between

    the amount of water and sodium transported over the peritoneal

    membrane. This dissociation occurs in the presence

    of aquaporin-mediated water transport. Sieving of sodium

    can be used as a rough measure for aquaporin-mediated

    water transport.

    Icodextrin contains glucose polymers, inducing ultrafiltration

    by colloid osmosis. Therefore, aquaporins play a

    minor role in ultrafiltration, which is confirmed by the absence

    of sodium sieving.

    Icodextrin is very suitable for the daytime dwell in children

    on a nightly intermittent peritoneal dialysis regimen.

    Ultrafiltration obtained with icodextrin is similar to ultrafiltration

    obtained with 3.86% glucose after a 12-hour

    dwell. When using icodextrin in children, it is also confirmed

    by the absence of sodium sieving that the aquaporins

    play a minor role in ultrafiltration...

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