what is "sodium sieving"?
it has to do with peritoneal dialysis but ive got no clue what it is!!!
- Anonymous9 years agoFavorite Answer
Sodium sieving is a consequence of dissociation between
the amount of water and sodium transported over the peritoneal
membrane. This dissociation occurs in the presence
of aquaporin-mediated water transport. Sieving of sodium
can be used as a rough measure for aquaporin-mediated
Icodextrin contains glucose polymers, inducing ultrafiltration
by colloid osmosis. Therefore, aquaporins play a
minor role in ultrafiltration, which is confirmed by the absence
of sodium sieving.
Icodextrin is very suitable for the daytime dwell in children
on a nightly intermittent peritoneal dialysis regimen.
Ultrafiltration obtained with icodextrin is similar to ultrafiltration
obtained with 3.86% glucose after a 12-hour
dwell. When using icodextrin in children, it is also confirmed
by the absence of sodium sieving that the aquaporins
play a minor role in ultrafiltration...