The causative agent of bubonic plague contains extra genes found on?
its cell wall
- 10 years agoFavorite Answer
"The corruption by three genes of a relatively benign recent ancestor of Y. pestis may have played a key role in the emergence of bubonic plague. Hinnebusch and colleagues, a plague expert team at the National Institutes for Health,8 maintains that the acquisition of two plasmid genes (i.e. just a few discrete genetic changes) in recent times changed the fairly harmless, Y. pseudotuberculosis, that causes mild food poisoning, to the agent of the ‘Black Death’. A third gene (carried on plasmid pMT1) produces murine toxin, an enzyme required for the initial survival of Y. pestis bacilli in the flea midgut .7 By acquiring this last gene from another organism, Y. pestis made a crucial shift in its host range, allowing it to survive in fleas, and devolved to relying on its blood-feeding host for transmission. This is just another example of the flexibility of many microbes in sometimes repackaging themselves into more dangerous agents of infectious disease."
so answer is plasmid.
- cubeloLv 44 years ago
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