I recently read Lost It by Kristen Tracy. There's definitely romance in it and it's a quirky book about first loves and, uh, as you probably guessed by the title, virginity, so it's a fun read.
I also read Almost Perfect by Brian Katcher - it's not exactly the usual teen romance, as it's about a boy who falls in love with a girl... and then finds out she's biologically a boy. It's really, truly well-written and a great read, I couldn't put the book down.
If you haven't already, read Stargirl by Jerry Spinelli. It's a bit of an easier read but it really is good. It's a bit weird as well, although completely in a good way, and Stargirl herself is a very entertaining and different character, as is their relationship.
In addition, there are a couple that aren't romance, but are really good - Speak by Laurie Halse Anderson, which is about a girl who struggles after being raped one night; and My Sister's Keeper, which I'm sure you've heard of. It's about a young girl who seeks to be medically emancipated from her family after spending her whole life in the hospital with her dying sister. It's a really emotional book, which is a lot coming from me as I don't normally get emotional with books.
EDIT: Also, I've never read many of them but I've heard from people that they're really good - if you want romance try Nicholas Sparks novels. (Dear John, The Last Song, A Walk to Remember, etc.) I'm not sure if they're about teens but I think they're mostly pretty young people in the books.