What is the difference between Mebendazole and Albendazole?
and can Mebendazole/Albendazole cause problems? any side-effects?
- AbeLincolnPartyLv 69 years agoBest Answer
Each drug has a similar spectrum of activity with Albendazole being preferred for strongyloidiasis and cystic hydatid disease caused by Echinococcus granulosus, and each has low systemic absorption.
Taking a fatty meal with Albendazole helps with absorption.
The drug Mebendazole is metabolized to inactive products by the liver (cimetidine inhibits metabolism, but often this is not actually done), but the drug Albendazole is metabolized to the active sulfoxide.
Both are usually safe for short term use, but long term use might cause liver problems, leukopenia, hair loss, headaches and fever (at least with albendazole) . Both induce liver metabolism of drugs.
Sometimes with antiworm therapy it is a good idea to take antihistamines or corticosteroids to suppress the allergic reaction to dead worms.Source(s): Goodman and Gilman's Pharmacological Basis of Therapeutics, 11th edition, pages 1078-1083.
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- fssLv 49 years ago
Mebendazole or MBZ is a benzimidazole. It is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms.
Mebendazole is thought to kill worms by selectively inhibiting the synthesis of microtubules, impairing the parasite's ability to utilise glucose.
usual dose : 100 mg tab twice a day for 3 days.(in all age groups)
The dosage may differ depending on which type of worm someone is infected with.
It is effective first line of treatment against:
usual dose 400 mg single dose(above 6 yr)
below 6 yr 200mg single dose
Threadworms or pinworms
this drug also used in various other diseases
Patients 60 kg or greater: 400 mg twice daily, with meals.
Patients less than 60 kg: 15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg).
Treatment interval: 28-day cycle followed by a 14-day albendazole-free interval, for a total of 3 cycles
- DeborahLv 44 years ago
Sounds like a Weekend at the Professor's house.
- 9 years ago
One starts with meb and the other alb