What is the difference between Mebendazole and Albendazole?

and can Mebendazole/Albendazole cause problems? any side-effects?

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  • 9 years ago
    Favorite Answer

    Each drug has a similar spectrum of activity with Albendazole being preferred for strongyloidiasis and cystic hydatid disease caused by Echinococcus granulosus, and each has low systemic absorption.

    Taking a fatty meal with Albendazole helps with absorption.

    The drug Mebendazole is metabolized to inactive products by the liver (cimetidine inhibits metabolism, but often this is not actually done), but the drug Albendazole is metabolized to the active sulfoxide.

    Both are usually safe for short term use, but long term use might cause liver problems, leukopenia, hair loss, headaches and fever (at least with albendazole) . Both induce liver metabolism of drugs.

    Sometimes with antiworm therapy it is a good idea to take antihistamines or corticosteroids to suppress the allergic reaction to dead worms.

    Source(s): Goodman and Gilman's Pharmacological Basis of Therapeutics, 11th edition, pages 1078-1083.
  • fisch
    Lv 4
    3 years ago

    Albendazole Vs Mebendazole

  • 4 years ago

    This Site Might Help You.

    RE:

    What is the difference between Mebendazole and Albendazole?

    and can Mebendazole/Albendazole cause problems? any side-effects?

    Source(s): difference mebendazole albendazole: https://tr.im/LMrZU
  • koeing
    Lv 4
    3 years ago

    Mebendazole Alternatives

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  • fss
    Lv 4
    9 years ago

    Mebendazole or MBZ is a benzimidazole. It is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms.

    Mebendazole is thought to kill worms by selectively inhibiting the synthesis of microtubules, impairing the parasite's ability to utilise glucose.

    usual dose : 100 mg tab twice a day for 3 days.(in all age groups)

    The dosage may differ depending on which type of worm someone is infected with.

    albendazole

    It is effective first line of treatment against:

    usual dose 400 mg single dose(above 6 yr)

    below 6 yr 200mg single dose

    Flatworms

    Flukes/trematodes

    Tapeworm/cestodes

    Echinococcosis

    Nematodes

    Hookworms

    Roundworms

    Whipworms

    Threadworms or pinworms

    this drug also used in various other diseases

    Hydatid disease

    Patients 60 kg or greater: 400 mg twice daily, with meals.

    Patients less than 60 kg: 15 mg/kg/day given in divided doses twice daily with meals (maximum total daily dose 800 mg).

    Treatment interval: 28-day cycle followed by a 14-day albendazole-free interval, for a total of 3 cycles

  • 4 years ago

    Sounds like a Weekend at the Professor's house.

  • 9 years ago

    One starts with meb and the other alb

    • Master5 years agoReport

      You're not very bright. Silly is the word.

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