breast, left, partial mastectomy---invasive ductal carcinoma, grade lll.
sentinel lymph node, dissection---no metastatic carcinoma.
report of immunohistochemical stains:
e-cadherin :positive for neoplastic cells.
estrogen receptors: positive
progesterone receptors: positive
the bottle 1 consists of a piece of breast tissue,4.5x3x2.8cm,emblemed by
suture stitchs .on serial sections, there is an ill-defined tumor lesios,
1.6x1.3cm,with gray tan and firm to hard in consistency within the central
focus . the basal and laterial margins are worrisome grossiy.
all for sampling with serial sections :
A,B,C1-2,D1-2,E1-2,F1-2,G and H.
(laterial side :two long stitchs :yellow-ink)
(nipple side: two short stitchs : blue-ink)
(head side :one long and one short stitchs : red -ink)
the bottle 2 consists of two pieces of firm nodular tissue, 0.4 and 0.6 cm.
all for section: I1-I2.
microscopic description :
1. histologic type:
invasive ductal carcinoma :score :8 , sbr grade:III
---tubular formation : (=3)< 10%
---nuclear pleomorphism:(=2) moderate
---mitotic rate (x40):(=3)>11 /10 hpf
(summing points :gradeI, 3-5 points: gradeII, 6-7 points:gradeIII, 8-9 points:)
2 surgical margin:
---(basal : black-ink):positive
---(superficial :green -ink):positive
---(laterial side :two long stitchs :yellow-ink):close(1mm)
---(nipple side: two short stitchs : blue-ink):free.
---(head side :one long and one short stitchs : red -ink):free
3 angiolymphatic invasion:
4 size of invasive carcinoma (microscopic):
----greatest dimension :1.4cm
5 sentinel node:
----negative for metastasis(0/2),proved by cytpkeratin.
6 immunohistochemical stains:
----(1)the neoplastic cells are positive for e - cadherin, invasive ductal
carcinoma is considered.
----(2) tumor cells are positive for estrogen receptors and progesterone
receptors:negative for her-2/neu.