威廉 asked in 科學生物學 · 1 decade ago

四個神經解剖的問題(急!!!)(20點)

這個是作業…….教授希望我們能找較新的journal 請麻煩註明出處

1. Give three one sentence reasons for the developmental disorder of Anencephaly. As a clue, there are several types of anencephaly, with different hypothesis about their causes.

2. Is there evidence that white matter within the central nervous system can regenerate? Is there evidence that grey matter within the central nervous system can regenerate?

3. Give a brief explanation of how the Basal ganglia (nuclei) are involved in thought disorders, such as schizophrenia.

4. Looking at the nervous system anatomy (from cellular to gross), how do you believe learning, or more simply, the storage of information can take place. This question is looking for you to put together a hypothesis of how anatomy/physiology of the system can be used to store bits of information.

P.S.1 第一題是希望能知道failure of anterior neural tube closure的原因

2 四題都要人類的

2 Answers

Rating
  • david
    Lv 5
    1 decade ago
    Favorite Answer

    1. The cause of anencephaly is disputed, neural tube defects do not follow direct patterns of heredity, though there is some indirect evidence of inheritance. Women taking certain medication, anencephaly and other physical and mental deformities have also been blamed on a high exposure to such toxins as lead, chromium, mercury, and nickel.

    2. White matter surround grey matter of cortex could regenerate. With aides of nutrition like Omega 3, DHA oil, it is easier to accomplish.3. Basal Ganglia is the source to secrete dopamine neurotransmitter. If Basal Ganglia were damaged, the dopamine concentration would not be balance in the brain. It could affect the body motion as well as the reward system. The schizophrenia prognosed would be lacking willness to perform some routine activities because of these loss of dopamine neurotransmitters.4. The anatomy or device imaging are scientific revealing the data of learning. We could judge by the fact we had observed to tell if that was a learning behavior.

  • ChiWen
    Lv 4
    1 decade ago

    1. Give three one sentence reasons for the developmental disorder of Anencephaly. As a clue, there are several types of anencephaly, with different hypothesis about their causes.

    解答:

    神經管畸形:

    是一種嚴重的畸形疾病,神經管就是胎兒的中樞神經系統。在胚胎的第15-17日開始,神經系統開始發育,至胚胎22日左右,神經褶的兩側開始互相靠攏,形成1個管道,稱為神經管,它的前端稱為神經管前孔,尾端稱為神經管後孔,胚胎在24-25日及26日時,前孔及後相繼關閉。胎兒神經管畸形主要表現為無腦兒、腦膨出、腦脊髓膜膨出、隱性脊柱裂、唇裂及齶裂等。

    神經管畸形發生原因:

    許多種類基因的表達或突變與神經系統發育、神經管畸形有關,

    (1)發育調節基因及轉錄因數類基因。

    (2)原癌基因和抑癌基因。

    (3)生長因數及其受體基因。

    (4)蛋白激酶C相關基因。

    (5)同型半胱氨酸代謝相關基因。

    (6)其他基因:細胞骨架

    2. Is there evidence that white matter within the central nervous system can regenerate? Is there evidence that grey matter within the central nervous system can regenerate?

    解答:

    現任台北榮民總醫院神經再生科主任鄭宏志 ( Henrich Cheng )領導的瑞典卡洛琳斯卡學院研究成員花了很多苦心以避免以往研究中犯的錯誤。他們把 34 隻白老鼠的胸椎第八節去掉四分之一英吋 (6.35mm) 的脊髓,擴大斷端間的距離,以便確定中間沒有任何神經組織存留。以防造成假性的成功。他們依照了一個非常精確的藍圖來建造這個橋梁。這個藍圖精確地區分了脊髓的白質與黑質兩種不同的神經組織。白質部分的神經都包著一層叫「神經鞘」的物質。這個物質的作用就好像是電線外層的絕緣體一樣。沒有絕緣體的部分則是灰質。白質幾乎是不可能再生的。但是要激發灰質的生長,相對來說,比較容易。

    來自(科學發展 2004 年 2 月, 374 期 65 頁)

    3. Give a brief explanation of how the Basal ganglia (nuclei) are involved in thought disorders, such as schizophrenia.

    解答:

    http://www.chem.pku.edu.cn/bianj/paper/07/7.pdf(%E...

    4. Looking at the nervous system anatomy (from cellular to gross), how do you believe learning, or more simply, the storage of information can take place. This question is looking for you to put together a hypothesis of how anatomy/physiology of the system can be used to store bits of information.

    解答:無固定答案,無法解答。

    參考文獻

    http://www.hudong.com/wiki/%E7%A5%9E%E7%B6%93%E7%A...

    http://baike.baidu.com/view/359107.htm(%E7%99%BE%E...

    http://web2.cc.nctu.edu.tw/~hcsci/hospital/sci/nas...

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