In clinics, patients with depression are usually
observed to be more than just suffering from a
bad mood, but also with low motivation and lack
of energy. Earlier, a study done by Christensen
and Duncan  showed that energy measures using
self-report questionnaire as predictors can distinguish
patients with major depression from those
without. In addition, Frank et al.  reported that
lacks of both motivation and energy are key symptoms
reported by patients who experience depression.
Although, the symptom of lack of energy
could be improved using antidepressant treatment,
their improvement may not be, as rapid as other
symptoms of major depressive disorder (MDD) .
Because the observed symptom of lacking
energy in MDD is important, several studies have
been conducted to investigate how those patients
improve with pharmaco-therapy. Patients treated
with fl uxoetine showed that compared with place
bo groups, they improve signifi cantly in retardation
factor (e.g., work and activity, retardation) of
the Hamilton Rating Scale for Depression (HAMD)
. Furthermore, the patients with energy-related
symptoms are improved with bupropion .
Patients with somatic symptoms are likely to seek
medical care, and the patients with fatigue symptom
are improved with bupropion . But, the
study attention has been drawn to investigate the
relation between energetic motivation and other
measurements, such as quality of life (QoL) and
patients’ self-rating of depression.
- 10 years agoBest Answer