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In clinics, patients with depression are usually observed to be more than just suffering from a bad mood, but also with low motivation and lack of energy. Earlier, a study done by Christensen and Duncan  showed that energy measures using self-report questionnaire as predictors can distinguish patients with major depression from those without. In addition, Frank et al.  reported that lacks of both motivation and energy are key symptoms reported by patients who experience depression. Although, the symptom of lack of energy could be improved using antidepressant treatment, their improvement may not be, as rapid as other symptoms of major depressive disorder (MDD) . Because the observed symptom of lacking energy in MDD is important, several studies have been conducted to investigate how those patients improve with pharmaco-therapy. Patients treated with fl uxoetine showed that compared with place bo groups, they improve signifi cantly in retardation factor (e.g., work and activity, retardation) of the Hamilton Rating Scale for Depression (HAMD) . Furthermore, the patients with energy-related symptoms are improved with bupropion . Patients with somatic symptoms are likely to seek medical care, and the patients with fatigue symptom are improved with bupropion . But, the study attention has been drawn to investigate the relation between energetic motivation and other measurements, such as quality of life (QoL) and patients’ self-rating of depression.
- bullLv 51 decade agoFavorite Answer
在診所裡,憂鬱症患者通常被認為不只為壞心情吃苦,而且也自主行動力低又缺乏活力.稍早Christensen 及 Duncan 所作的一項研究顯示用自我報告問卷調查作預測的活力評量可以從無病者裡過濾分辨出主要憂鬱症患者.除此之外Frank等人報告說缺乏自主行動及缺乏活力是顯現在有憂鬱經驗的病患上的關鍵症候.雖然缺乏活動力的症候可以用抗憂鬱藥物療法改進,他們的改進可能不像其他主要憂鬱失調(MDD)症候一樣快速 .因為在MDD裡觀查到的缺乏活動力症候是重要的,有一些研究曾經被導向去調查那些病患如何因藥物治療而改進.用fl uxoetine治療的病人與使用placebo(安慰劑)群比較,他們顯著的改善了漢彌爾頓憂鬱症級別(HAMD)的遲礙現像(就是工作及活力遲礙) .還有,有與活動力有關症候的患者因使用抗抑鬱藥 (Bupropion)而改善.有軀體症狀的病人可能要找醫療照顧,而有倦怠症候的患者則用抗抑鬱藥 (Bupropion)改善.但是,研究焦點被帶往調查能量自動力與其他一些測量之間的關係,諸如生活品質(QoL)及患者憂鬱症的自我分級.Source(s): ccrE