Anonymous
Anonymous asked in Science & MathematicsBiology · 10 years ago

What is the function of primase?

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  • 10 years ago
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    Primase is an enzyme that creates a short RNA sequence, called a primer, on a DNA template strand so that DNA polymerase can make a copy of that DNA strand.

    DNA polymerases cannot synthesize a DNA strand de novo: they can only extend an already existing strand. So the RNA primase enzyme lays down a short RNA primer completement to the DNA strand being copied, then DNA polymerase extends the new strand. Therefore, primase must lay down one RNA primer for each Okazaki fragment synthesized on a lagging strand, as well as one RNA primer for each start of synthesis on a leading strand.

    PS: Another DNA polymerase later removes the RNA primers and replaces them with DNA, followed by DNA ligase joining the backbones to finish the job.

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  • 4 years ago

    It's false. Primase catalyzes the synthesis of a short RNA segment (called a primer) complementary to a ssDNA template. Primase is of key importance in DNA replication because no known DNA polymerases can initiate the synthesis of a DNA strand without an initial RNA or DNA primer (for temporary DNA elongation). So it does the opposite :)

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  • 3 years ago

    Dna Primase

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  • Jamie
    Lv 4
    4 years ago

    For the best answers, search on this site https://shorturl.im/W47Rh

    False. Primase synthesizes RNA primers, which are need for DNA polymerase to synthesize DNA. Basically, DNA polymerase can't start from scratch, so it needs RNA primers and build from there.

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  • Anonymous
    5 years ago

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    What is the function of primase?

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  • Anonymous
    10 years ago

    Primase is an enzyme that catalyse the synthesis of a short sequence of single strand RNA ( RNA primer) on which the polymerase enzyme started forming Okazaki fragements to make a new copy of the DNA gene.

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  • 3 years ago

    Primase Definition

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  • Anonymous
    10 years ago

    primase is an enzyme that add a sequence of RNA allowing the DNA polymerase 3 to begin working on the dna strand.

    uhmmmm don't pay attention to the lady below me. okazaki fragments are only made on the 3'-5' direction.... Not on the 5'-3' so you only make okazaki fragments on 2 location per replication bubble, not on all 4 sites.... You failed lady.

    • magnolia
      Lv 4
      6 years agoReport

      Yeah this is correct!

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