Before taking this medicine
Do not use Wellbutrin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
You should not take Wellbutrin if you are allergic to bupropion, or if you have:
- epilepsy or a seizure disorder;
- an eating disorder such as anorexia or bulimia; or
- if you have suddenly stopped using alcohol, seizure medication, or a sedative (Valium, Nembutal, Seconal, Solfoton, and others).
Wellbutrin may cause seizures, especially in people with certain medical conditions. Tell your doctor about all of your medical conditions.
Do not take Wellbutrin to treat more than one condition at a time. If you take this medicine for depression, do not also take Zyban to quit smoking.
To make sure this medicine is safe for you, tell your doctor if you have:
- a history of head injury, seizures, or brain or spinal cord tumor;
- narrow-angle glaucoma;
- heart disease, high blood pressure, history of heart attack;
- kidney or liver disease (especially cirrhosis); or
- bipolar disorder (manic depression).
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Wellbutrin. Your family or other caregivers should also be alert to changes in your mood or symptoms.
FDA pregnancy category C. It is not known whether Wellbutrin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
See also: Pregnancy and breastfeeding warnings (in more detail)
Bupropion can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.
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