Plum juice, but not dried plum powder, is effective in mitigating
cognitive deficits in aged rats
Objective: Normal aging in animals and humans is accompanied by a decline in cognitive performance that is thought to be due to the long-term effects of oxidative stress and inflammation on neurologic processes. Previous findings have suggested that protection against age-related cognitive declines may be achieved by increasing the dietary intake of fruits and vegetables, especially those that are high in antioxidant activity, such as blueberries and strawberries. The objective of this study was to investigate supplementation with Prunus domestica L. in mitigating age-related deficits in cognitive function.
Methods: We investigated the effects of supplementation with P. domestica L.（野櫻桃李）, consumed as a 2% dried plum (i.e., prune) powder or 100% plum juice for 8 wk, in mitigating age-related deficits in cognitive function in aged Fischer 344 rats.
Results: Rats that drank plum juice from 19 to 21 mo of age had improved working memory in the Morris water maze, whereas rats fed dried plum powder were not different from the control group,possibly due to the smaller quantity of phenolics consumed in the powder group compared with the juice group.
Conclusion: These results are discussed in relation to the amount and type of phenolics present in the plum products and in relation to other dietary intervention studies in which cognitive benefits have been reported.
題目的Plum juice/ dried plum powder
2% dried plum的 2％是指什麼意思呢？
LATENCY TO PLATFORM (SEC)
下面這段裡的*P 0.01, t test是什麼意阿..圖表常會出現
Fig. 1. Morris water maze performance assessed as latency (mean SEM)
to find the hidden platform over the 4 d of testing. Means not sharing a
common letter are significantly different from each other (P 0.05,
Fisher’s least significant
difference test). There was a difference (i.e., an improvement) between trial 1 and trial 2 performance for the plum juice group (**P 0.01, t test), meaning that the plum juice group had improved working memory. This improvement was not seen in the control or the prune diet rats.
- 冰山冷燕Lv 41 decade agoFavorite Answer