Gerol asked in 健康心理健康 · 1 decade ago

什麼是錐體外反應?有咩症狀?

什麼是錐體外反應?有咩症狀?

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  • 1 decade ago
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    錐體外系症狀(extrapyramidal symptoms) 係抗精神病藥物治療最常見的神經系統副作用,以類帕金森氏症最為常見。

    表現為運動不能、肌張力高、震顫和自主神經功能紊亂等。藥源性錐體外系反應在臨床上尤常見,臨床表現與帕金森病相似,有動作遲緩,肌肉張力增高,面容呆板,流涎等。

    有多種常用藥具有引起錐體外系反應副作用的藥物,如非那根、咳必清、阿托品、胃覆安、甲硝唑、西米替丁、氯丙嗪、奮乃靜等。這些藥物都可在一定程度上產生錐體外系興奮作用,並可導致中樞神經系統對錐體外系的控制失調,使得錐體外系興奮性增強,結果由錐體外系控制的肌力和肌緊張度失控,從而引起一系列與肌力和肌緊張相關的症狀和體征。

    藥源性錐體外系反應是完全可以有效預防的,關鍵在於要遵醫囑用藥,不要輕易加大用藥劑量,更不要隨意買藥來服用。如果出現異常就要與醫生及時取得聯系。

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    Extrapyramidal symptoms (also known as EPS) are a set of side effects that are common with antipsychotic medications, as well as with a few other types of medications. Antipsychotics are prescription medications used to treat psychotic disorders, such as schizophrenia, schizoaffective disorder, or psychotic depression.

    Extrapyramidal symptoms are usually divided into different categories. Dyskinesias are movement disorders, while dystonias are muscle tension disorders. "Tardive" symptoms are those that appear during long-term treatment (often after several years). Unlike earlier symptoms, tardive symptoms are more likely to be permanent even after the medication is stopped.

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