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What relation do COX meds have w/ NSAIDs?

Non-steroidal anti-inflammatory (NSAIDs)

COX

What relationship do they have to eachother?

Thakns in advance!

1 Answer

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  • 1 decade ago
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    NSAIDs are inhibitors of the enzymes COX(Cyclo-oxygenase).

    COX enzymes are responsible for the production of prostaglandins, prostacyclins & leukotrienes. Prostaglandins are involved in inflammation, pyrexia & pain generation, so COX inhibitors have use as anti inflammatory, anti pyretic & analgesic drugs. e.g: diclofenac sodium, ibuprofen

    So I guess by COX drugs you mean COX inhibitors, in which case it is synonymous with NSAIDs.

    Also there is a relatively new class of drugs which specifically inhibit COX2 enzyme. These have relatively less side effects than non-selective COX inhibiting NSAIDs.

    Hope that helped.

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    http://rajamed.blogspot.com

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