asked in 健康疾病與處置傳染病 · 1 decade ago

HPV 52 +++++ 5個加 請問可以治療並完全好嗎?

我一個很要好的朋友,因為當初交了一個男友,對方隱瞞自身有問題,結果得了菜花,起初以為是自己的問題,所以自行擦藥,後來想說2人既然有並那就不要害人,也沒有去看醫生,就這樣持續了5年多,結果分手了...之後決定去看醫生做檢驗,發現HPV 52 +++++,現在很絕望

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  • Anonymous
    1 decade ago
    Favorite Answer

    The present invention also relates to a process for expressing an HPV 52 L1 protein in a recombinant host cell, comprising: (a) introducing a vector comprising a nucleic acid encoding an HPV 52 L1 protein into a yeast host cell; and (b) culturing the yeast host cell under conditions which allow expression of said HPV 52 L1 protein.The present invention further relates to a process for expressing an HPV 52 L1 protein in a recombinant host cell, comprising: (a) introducing a vector comprising a nucleic acid molecule encoding an HPV 52 L1 protein into a yeast host cell; wherein the nucleic acid molecule is codon-optimized for optimal expression in the yeast host cell and; (b) culturing the yeast host cell under conditions which allow expression of said HPV 52 L1 protein.

    2009-09-28 14:24:56 補充:

    In preferred embodiments, the nucleic acid molecule comprises a sequence of nucleotides as set forth in SEQ ID NO: 1 (designated herein “52 L1 R sequence”).

    2009-09-28 14:25:29 補充:

    This invention also relates to HPV 52 virus-like particles (VLPs) which are produced in yeast cells, methods of producing HPV 52 VLPs, and methods of using HPV 52 VLPs.

    2009-09-28 14:26:15 補充:

    In a preferred embodiment of the invention, the yeast is selected from the group consisting of: Saccharomyces cerevisiae, Hansenula polymorpha, Pichia pastoris, Kluyvermyces fragilis, Kluveromyces lactis, and Schizosaccharomyces pombe.

    2009-09-28 14:26:38 補充:

    Another aspect of this invention is an HPV 52 VLP, wherein the VLP is produced by recombinant expression of HPV 52 L1 or HPV 52 L1+L2 in a yeast cell.

    2009-09-28 14:26:43 補充:

    Another aspect of this invention is an HPV 52 VLP, wherein the VLP is produced by recombinant expression of HPV 52 L1 or HPV 52 L1+L2 in a yeast cell.

    2009-09-28 14:26:59 補充:

    Yet another aspect of this invention is an HPV 52 VLP which comprises an HPV 52 L1 protein produced by a codon-optimized HPV 52 L1 gene. In an exemplary embodiment of this aspect of the invention, the codon-optimized HPV 52 L1 gene comprises a sequence of nucleotides as set forth in SEQ ID NO: 1.

    2009-09-28 14:27:23 補充:

    This invention also provides a method for inducing an immune response in an animal comprising administering HPV 52 virus-like particles to the animal. In a preferred embodiment, the HPV 52 VLPs are produced by a codon-optimized gene.

    2009-09-28 14:27:45 補充:

    Yet another aspect of this invention is a method of preventing or treating HPV-associated cervical cancer comprising administering to a mammal a vaccine comprising HPV 52 VLPs. In a preferred embodiment of this aspect of the invention, the HPV 52 VLPs are produced in yeast.

    2009-09-28 14:28:07 補充:

    This invention also relates to a vaccine comprising HPV 52 virus-like particles (VLPs), wherein the HPV 52 VLPs are produced in yeast.

    2009-09-28 14:29:26 補充:

    All Treatments

    Prescription Treatment

    Aldara

    Condylox

    2009-09-28 14:30:26 補充:

    Genital Wart Treatment

    Amoils

    DermaTend

    Dermisil

    Terrasil

    Wartfreee

    Wartrol

    Wartsol

    2009-09-28 14:31:00 補充:

    Immune System Control

    Dermisil Naturasil

    ImmunityPlus

    Liquid Zeolite

    Viratrol

    2009-09-28 14:31:03 補充:

    Immune System Control

    Dermisil Naturasil

    ImmunityPlus

    Liquid Zeolite

    Viratrol

    2009-09-28 14:32:33 補充:

    Amoils..

    The effectiveness of Heal Warts to treat genital warts and HPV - the Human Papilloma Virus - including anal, vaginal, body & genital warts, in both men or women, is unsurpassed. ...........

    2009-09-28 14:33:55 補充:

    There are about 80 types of human papilloma virus. Genital warts are caused by HPV types 6, 11, 16, 18, 30, 42, 43, 44, 45, 51, 52 and 54.

    2009-09-28 14:34:04 補充:

    Types 6 and 11 are responsible for 90% of genital warts cases. HPV also causes many cases of cervical cancer and probably most of anal cancer cases; types 16 and 18 account for 70% of cases.

    2009-09-28 14:34:33 補充:

    A sudden and strong eruption of genital warts could suggest a defect in their bodies immune system perhaps caused by another serious illness.

    2009-09-28 14:36:17 補充:

    The present invention relates generally to the prevention and/or therapy of human papillomavirus (HPV) infection. More specifically, the present invention relates to synthetic polynucleotides encoding HPV 52 L1 protein,

    2009-09-28 14:36:32 補充:

    and to recombinant vectors and hosts comprising said polynucleotides. This invention also relates to HPV 52 virus-like particles (VLPs),

    2009-09-28 14:36:41 補充:

    wherein the VLPs are produced by expressing recombinant HPV 52 L1 or L1+L2 in yeast cells and to their use in vaccines and pharmaceutical compositions for preventing and treating HPV infections.

    2009-09-28 14:37:32 補充:

    BACKGROUND OF THE INVENTION

    There are more than 80 types of human papillomavirus (HPV), many of which have been associated with a wide variety of biological phenotypes,

    2009-09-28 14:37:41 補充:

    from benign proliferative warts to malignant carcinomas (for review, see McMurray et al., Int. J. Exp. Pathol. 82(1): 15-33 (2001)).

    2009-09-28 14:38:05 補充:

    HPV6 and HPV11 are the types most commonly associated with benign warts, nonmalignant condyloma acuminata and/or low-grade dysplasia of the genital or respiratory mucosa

    2009-09-28 14:39:22 補充:

    HPV16 and HPV18 are the high-risk types most frequently associated with in situ and invasive carcinomas of the cervix, vagina, vulva and anal canal.

    2009-09-28 14:39:28 補充:

    More than 90% of cervical carcinomas are associated with infections of HPV16, HPV18 or the less prevalent oncogenic types HPV31, -33, -45, -52 and -58 (Schiffman et al., J. Natl. Cancer Inst. 85(12): 958-64 (1993)).

    2009-09-28 14:39:47 補充:

    The observation that HPV DNA is detected in 90-100% of cervical cancers provides strong epidemiological evidence that HPVs cause cervical carcinoma (see Bosch et al., J. Clin. Pathol. 55: 244-265 (2002)).

    2009-09-28 14:40:40 補充:

    Papillomaviruses are small (50-60 nm), nonenveloped, icosahedral DNA viruses that encode up to eight early and two late genes. The open reading frames (ORFs) of the viral genomes are designated E1 to E7

    2009-09-28 14:41:00 補充:

    and L1 and L2, where “E” denotes early and “L” denotes late. L1 and L2 code for virus capsid proteins, while the E genes are associated with functions such as viral replication and cellular transformation.

    2009-09-28 14:41:21 補充:

    The L1 protein is the major capsid protein and has a molecular weight of 55-60 kDa. The L2 protein is the minor capsid protein. Immunological data suggest that most of the L2 protein is internal to the L1 protein in the viral capsid.

    2009-09-28 14:41:38 補充:

    Both the L1 and L2 proteins are highly conserved among different papillomaviruses.

    2009-09-28 14:42:17 補充:

    Expression of the L1 protein or a combination of the L1 and L2 proteins in yeast, insect cells, mammalian cells or bacteria leads to self-assembly of virus-like particles (VLPs)

    2009-09-28 14:42:18 補充:

    Expression of the L1 protein or a combination of the L1 and L2 proteins in yeast, insect cells, mammalian cells or bacteria leads to self-assembly of virus-like particles (VLPs)

    2009-09-28 14:42:28 補充:

    (for review, see Schiller and Roden, in Papillomavirus Reviews: Current Research on Papillomaviruses; Lacey, ed. Leeds, UK:

    2009-09-28 14:42:50 補充:

    Leeds Medical Information, pp 101-12 (1996)). VLPs are morphologically similar to authentic virions and are capable of inducing high titres of neutralizing antibodies upon administration into animals or humans.

    2009-09-28 14:42:51 補充:

    Leeds Medical Information, pp 101-12 (1996)). VLPs are morphologically similar to authentic virions and are capable of inducing high titres of neutralizing antibodies upon administration into animals or humans.

    2009-09-28 14:43:40 補充:

    Because VLPs do not contain the potentially oncogenic viral genome, they present a safe alternative to the use of live virus in HPV vaccine development (for review, see Schiller and Hidesheim, J. Clin. Virol. 19: 67-74 (2000)).

    2009-09-28 14:44:02 補充:

    For this reason, the L1 and L2 genes have been identified as immunological targets for the development of prophylactic and therapeutic vaccines for HPV infection and disease.

    2009-09-28 14:44:54 補充:

    HPV vaccine development and commercialization have been hindered by difficulties associated with obtaining high expression levels of capsid proteins in successfully transformed host organisms, limiting the production of purified protein.

    2009-09-28 14:47:13 補充:

    Therefore, despite the identification of wild-type nucleotide sequences encoding HPV L1 proteins such as HPV 52 L1 protein,

    2009-09-28 14:47:20 補充:

    it would be highly desirable to develop a readily renewable source of crude HPV L1 protein that utilizes HPV 52 L1-encoding nucleotide sequences that are optimized for expression in the intended host cell

    2009-09-28 14:47:41 補充:

    Additionally, it would be useful to produce large quantities of HPV 52 L1 VLPs having the immunity-conferring properties of the native proteins for use in vaccine development.

    2009-09-28 14:53:48 補充:

    Dr. Silvia de Sanjose and colleagues

    They reviewed 1466 penile carcinoma samples. Of these, 46.9% were associated with HPV. The HPV subtypes included HPV-16 (60.23%), HPV-18 (13.35%), HPV 6/11 (8.13%), HPV-31 (1.16%), HPV-45 (1.16%), HPV-33 (0.97%), HPV-52 (0.58%), and other types (2.47%).

    2009-09-28 14:58:07 補充:

    免疫治療是女性HPV或子宮頸異常的可能治療選項之一

    2009-09-28 15:00:48 補充:

    November 14, 2006 (New York) –- Merck's recently approved prophylactic human papillomavirus (HPV) vaccine (Gardasil) has been largely welcomed by the medical community, but the product is reportedly not useful for women who already have HPV

    2009-09-28 15:01:07 補充:

    As a result, researchers are now exploring the possibilities of therapeutic vaccines. The New York Cancer Consortium recently completed a National Cancer Institute–sponsored study evaluating one such product and presented findings here at the Chemotherapy Foundation Symposium XXIV.

    2009-09-28 15:01:24 補充:

    The vaccine is called SGN-00101 (HspE7, Stressgen Biotechnologies, Collegeville, Pennsylvania). In this single-arm, open-label, phase 2 study, the researchers looked at 57 women with grade 3 cervical intraepithelial neoplasia.

    2009-09-28 15:01:51 補充:

    "The gold standard for treatment of high-grade cervical intraepithelial neoplasia is extirpative therapy," Mark Einstein, MD, from the Albert Einstein College of Medicine and Cancer Center, in New York

    2009-09-28 15:02:07 補充:

    said during his presentation at the meeting. "However, surgical management does not eradicate human papillomavirus, the causative agent for all cervical cancer from the genital tract."

    2009-09-28 17:06:18 補充:

    Human papillomaviruses are DNA viruses thatinfect epithelial (skin or mucosal) cells. There

    are more than 100 known HPV genotypes, whichare numbered in order of their discovery. 9

    2009-09-28 17:06:42 補充:

    但對於其所引起的子宮頸癌前病變和菜花,可以局部治療

    2009-09-28 17:07:26 補充:

    At least 13 HPV genotypes can cause cancer.10• The two genotypes most commonly associated

    with cervical cancer are genotypes 16 and 18.

    2009-09-28 17:08:02 補充:

    HPV genotypes that infect the genital mucosa areconsidered “high-risk” or “low-risk”, according to their link with cancer.11

    2009-09-28 17:08:25 補充:

    The high-risk genotypes– genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56,

    58, 59 and 66 – can lead to cervical cancer,

    2009-09-28 17:10:23 補充:

    子宮頸癌在有接受手術或是放射線治療、化學治療的生物預測因子的檢查,其人類乳狀突病毒的基因分型與其預後的研究,全世界如火如塗爭相研發,例如Higgin、Burger、Lambard、Schwartz et al各國的學者利用各種分子生物技術

    2009-09-28 17:10:30 補充:

    In situ RNA probe、L1PCR/MY09,MY11、SBH/L1PCR、各種E2,E6,E7、Type specific PCR、L1PCR/MY09,MY11 E6 type specific PCR分別刊出於超A級的醫學文獻1991 Lancet、1996 JNCI、1998 JCO、2001 JCO的四月號,人類乳狀突病毒的檢出率80.2 至85.7﹪

    2009-09-28 17:11:32 補充:

    共同認定

    HPV-18對於子宮頸癌的預後較差,有些可能與早期的子宮頸癌有關,而與較晚期的子宮頸癌無關。Leminen、Kristesen、van Muyden等,少數的學者認為人類乳狀突病毒的基因分型與其預後無關;

    2009-09-28 17:11:40 補充:

    在這些研究人類乳狀突病毒的基因分型Schwartz 在臨床腫瘤雜誌(JCO)目前醫學史上最大的樣本數目,van Muyden在1999癌症雜誌(Cancer)使用65 base pair較短的多鏈脢反應之後再用直接定序(direct sequencing)或排列探針分析(line probe assay; LiPA)在石蠟包埋的子宮頸癌檢測出100﹪HPV DNA。

    2009-09-28 17:12:48 補充:

    國防醫學院廖凱莉教授使用美國人民來做的人類乳狀突病毒的基因分型證實含高度分化不良的子宮頸癌或癌前期病變有91.7﹪的陽性反應;她也使用台灣人民來做的人類乳狀突病毒的基因分型證實高度分化不良的子宮頸癌或癌前期病變有89﹪的陽性反應,其中以HPV-16為最大部分佔有50﹪,

    2010-01-04 23:52:08 補充:

    陳建仁教授的分析結果顯示,在LSIL 與HSIL 的癌前病變階段,HPV52、58型具有較明顯的相關意義,但是要轉變形成侵襲癌, HPV16、18型仍為多數的主要型別

    2010-01-04 23:52:56 補充:

    尖锐湿疣复发最常出现于治疗后3个月内,随着时间的延长,病人传染性降低,复发的可能性亦降低。患者经治疗后6个月不复发,就算临床治愈了。优亭康搭档对于尖锐湿疣的防复发治疗效果很好。这期间要注意严格消毒处理,避免交叉感染和预防反复。建议你3个月后来医院复查一下,6个月后来医院做一下癌前病变筛查以把握病情的发展

    2010-01-04 23:55:28 補充:

    可以治療,只是要花費很多時間與耐心,

    現金醫院大概就是門診手術治療與藥物搭配,

    若是能夠尋找中醫治療,大概可以有生機,

    中醫醫術領先全球,食物搭配中醫藥膳都是很棒的方法!

    2010-01-04 23:57:36 補充:

    台灣婦女子宮頸癌病患中並不常見到HPV 52型和58型病毒DNA嵌入到人類基因體中,可見病毒52型和58型其DNA嵌入宿主基因體並非是子宮頸癌發展必須的因素。相反的,16型及18型病毒DNA嵌入宿主基因體是導致子宮頸癌非常重要的步驟。而16、18、52型的高E6病毒量,則具有預測高度細胞病變轉變至子宮頸癌的能力。可見HPV DNA是否嵌入宿主基因體和其病毒量,在子宮頸癌癌化過程中,可能因病毒型別的差異而扮演不同的角色。在此研究中我

    2010-01-06 23:34:12 補充:

    人乳头状瘤病毒非常常见,可以通过性行为传播。

    经研究发现,它是导致女性子宫颈癌的主要原因。

    据统计,75%以上的有性能力的成年人在生命中的某个阶段体内都会有这种病毒。通常这种感染是一过性的,在几个月内会逐渐消失,而不会引起任何的症状或造成长期的影响。

    HPV感染的流行因素

    2010-01-06 23:34:34 補充:

    由于HPV感染通常没有明显的临床症状,其检出率因各种方法而异,对于HPV感染流行因素的分析就很难确定。但HPV感染是一种性传播疾病,与性行为因素有关,这一点已经明确。而个体的卫生状况好,注意经期卫生,同房前后卫生,使用宫内避孕环等均可以使感染HPV的几率降低。

    (1)性行为:大部分研究表明妇女近期的性伴侣数,性交频率,性伴侣患有生殖道疣等均与HPV感染密切相关。尽管有些研究表明初次性交年龄与HPV感染也有关,但这种因素受性伴侣数的影响,调整性伴侣数后,其危险性无显著性意义。

    2010-01-06 23:34:44 補充:

    (2)免疫因素:宿主的免疫力对HPV感染及病变的进展有很大的作用。有研究发现肾移植的免疫抑制者HPV的感染率是正常人群的17倍。HIV感染的人群中HPV感染率也增高。由于HIV感染人群性行为比较混乱,伴侣数较多,初次性交年龄小等因素,使HPV感染几率增加。但有些研究并不能证明免疫抑制与HPV感染有直接的相关性,HIV人群可能由于自身暴露的危险性高或机体抵御潜伏病毒的能力降低而使HPV感染率增高,这一人群的HPV DNA检出水平高于正常人群,这表明机体抑制HPV感染的能力降低。

    2010-01-06 23:34:55 補充:

    (3)怀孕:有研究表明,妇女怀孕次数增多,分娩次数,流产次数等并不增加HPV感染的危险性,畸胎的个数却与HPV感染相关。有些研究表明孕期妇女HPV感染率高,而且病毒检出量也增高,但这可能是由于孕期病毒水平增高而使检出效率提高所致。一项应用PCR法检测HPV的研究证实了这一观点,PCR法检测HPV病毒不依赖病毒的含量,结果发现孕期与非孕期妇女的感染率无显著差(9.6%/10.9%)。

    2010-01-06 23:35:06 補充:

    (4)口服避孕药:尽管口服避孕药可以增加宫颈癌的危险性,但它是否影响HPV感染还存在很大争议。有研究表明口服避孕药确实能增加HPV感染的几率,但有人认为口服避孕药对宫颈低度病变的发生无影响,却可以增加高度病变的危险性,因此认为口服避孕药是通过改变疾病的进展状态,而不是直接影响HPV感染率。

    总之,生殖道HPV感染是一种常见的性传播疾病。性活跃妇女可能有50%感染过至少一种型别的HPV。由于HPV感染是宫颈癌的病因,因此必须重视这种感染,加强HPV病毒疫苗的研制,消除其对人类的危害。

    2010-01-06 23:36:11 補充:

    治疗

    由于目前没有特效的抗病毒药物,尖锐湿疣的治疗必须采用综合治疗.

    (一)治疗诱因:(白带过多,包皮过长、淋病).

    (2)提高机体免疫力.

    (3)应用抗病药物.一般只要坚持规则的综合治疗都可治愈.

    2010-01-06 23:36:28 補充:

    1.手术疗法

    对于单发、面积小的湿疣,可手术切除;对巨大尖锐湿疣,可用Mohs氏手术切除,手术时用冷冻切片检查损害是否切除干净.

    2.冷冻疗法

    利用-196℃低温的液体氮,采用压冻法治疗尖锐湿疣,促进疣组织坏死脱落,本法适用于数量少,面积小的湿疣,可行1-2次治疗,间隔时间为一周.

    3.激光治疗

    通常用CO2激光,采用烧灼法治疗尖锐湿疣,本疗法最适用女阴、阴茎或肛周的湿疣.对单发或少量多发湿疣可行一次性治疗,对多发或面积大的湿疣可行2-3次治疗,间隔时间一般为一周.

    2010-01-06 23:36:44 補充:

    4.电灼治疗

    采用高频电针或电刀切除湿疣.方法:局部麻醉,然后电灼,本疗法适应数量少,面积小的湿疣.

    5.微波治疗

    采用微波手术治疗机,利多卡因局麻,将杆状辐射探头尖端插入尖锐湿直达疣体基底,当看到就体变小、颜色变暗、由软变硬时,则热辐射凝固完成,即可抽出探头.凝固的病灶可以用镊子挟除.为防止复发,可对残存的基底部重复凝固一次.

    6.β-射线治疗

    我们应用β-射线治疗尖锐湿疣取得了较为满意的效果,该方法疗效高,无痛苦、无损伤、副作用少,复发率低,在临床上有推广价值.

    2010-01-06 23:36:57 補充:

    7.药物疗法

    (1)足叶草脂:本疗法适用湿润区域的湿疣,例如发生于包皮过长而未曾作包皮环切除手术的龟头及会阴部的湿疣.但对宫颈尖锐湿疣不能用足叶草脂治疗.用20%足叶草脂酊剂涂到皮损处或用药前,先有油质抗菌药膏保护皮损周围的正常皮肤或粘膜,然后涂药,用后4-6小时,用30%硼酸水或肥皂水清洗,必要时3天后重复用药,该药是国外用于本病治疗的首先药,一般用一次可愈.但有很多缺点,如对组织破坏性大,使用不当可引起局部溃疡.毒性大,主要表现为恶心、肠梗阻、白细胞及血小板减少,心动过速、尿闭或少尿,故使用时必须谨慎,发现上述反应时,应立即停药.

    2010-01-06 23:37:19 補充:

    2)抗病毒药:可用5%酞丁胺霜剂,或用0.25%疱疹净软膏,每日2次,外涂.无环鸟苷口服,每日5次,每次200mg,或用其软膏外用,α-干扰素每日注射300万单位,每周用药5天.或干扰素300万单位注入疣体基部,每周2次.连用2-3周,主要副作用为流感样综合症,局部用药副作用较少且轻微.

    2010-01-21 20:43:00 補充:

    治疗

    由于目前没有特效的抗病毒药物,尖锐湿疣的治疗必须采用综合治疗.

    (一)治疗诱因:(白带过多,包皮过长、淋病).

    (2)提高机体免疫力.

    (3)应用抗病药物.一般只要坚持规则的综合治疗都可治愈.

    1.手术疗法

    对于单发、面积小的湿疣,可手术切除;对巨大尖锐湿疣,可用Mohs氏手术切除,手术时用冷冻切片检查损害是否切除干净.

    2.冷冻疗法

    利用-196℃低温的液体氮,采用压冻法治疗尖锐湿疣,促进疣组织坏死脱落,本法适用于数量少,面积小的湿疣,可行1-2次治疗,间隔时间为一周.

    2010-01-21 20:43:25 補充:

    3.激光治疗

    通常用CO2激光,采用烧灼法治疗尖锐湿疣,本疗法最适用女阴、阴茎或肛周的湿疣.对单发或少量多发湿疣可行一次性治疗,对多发或面积大的湿疣可行2-3次治疗,间隔时间一般为一周.

    4.电灼治疗

    采用高频电针或电刀切除湿疣.方法:局部麻醉,然后电灼,本疗法适应数量少,面积小的湿疣.

    5.微波治疗

    采用微波手术治疗机,利多卡因局麻,将杆状辐射探头尖端插入尖锐湿直达疣体基底,当看到就体变小、颜色变暗、由软变硬时,则热辐射凝固完成,即可抽出探头.凝固的病灶可以用镊子挟除.为防止复发,可对残存的基底部重复凝固一次.

    2010-01-21 20:43:57 補充:

    6.β-射线治疗

    我们应用β-射线治疗尖锐湿疣取得了较为满意的效果,该方法疗效高,无痛苦、无损伤、副作用少,复发率低,在临床上有推广价值.

    7.药物疗法

    2010-01-21 20:44:09 補充:

    (1)足叶草脂:本疗法适用湿润区域的湿疣,例如发生于包皮过长而未曾作包皮环切除手术的龟头及会阴部的湿疣.但对宫颈尖锐湿疣不能用足叶草脂治疗.用20%足叶草脂酊剂涂到皮损处或用药前,先有油质抗菌药膏保护皮损周围的正常皮肤或粘膜,然后涂药,用后4-6小时,用30%硼酸水或肥皂水清洗,必要时3天后重复用药,该药是国外用于本病治疗的首先药,一般用一次可愈.但有很多缺点,如对组织破坏性大,使用不当可引起局部溃疡.毒性大,主要表现为恶心、肠梗阻、白细胞及血小板减少,心动过速、尿闭或少尿,故使用时必须谨慎,发现上述反应时,应立即停药.

    2010-01-21 20:44:41 補充:

    2)抗病毒药:可用5%酞丁胺霜剂,或用0.25%疱疹净软膏,每日2次,外涂.无环鸟苷口服,每日5次,每次200mg,或用其软膏外用,α-干扰素每日注射300万单位,每周用药5天.或干扰素300万单位注入疣体基部,每周2次.连用2-3周,主要副作用为流感样综合症,局部用药副作用较少且轻微.

    2010-01-21 20:44:49 補充:

    (3)腐蚀剂或消毒剂:常用有30%-50%3氯醋酸或饱和2氯醋酸,或18%过氧乙酸.用10%水杨酸冰醋酸或40%甲醛、2%液化酚、75%乙醇蒸馏水100ml混合溶液,点涂局部,用于龟头、肛周湿疣,每日或隔日一次,效果甚好.消毒剂可用20%碘酊外涂,或2.5-5%碘酊注射于疣体基部,每次0.1-1.5ml,或用新洁尔灭外涂或以0.1-0.2%外敷,后者需配合全身疗法.

    2010-01-21 20:45:16 補充:

    4)抗癌药

    ①5-氟脲嘧啶(5-Fu):一般外用5%软膏或霜剂,每日2次,3周为一疗程.2.5%~5%氟脲嘧啶湿敷治疗阴茎、肛周尖锐湿疣,每次敷20分钟,每日一次,6次为一疗程.也可用聚乙2醇作基质,加入占其干质5%的5-Fu粉剂制成栓剂,治疗男女尿道内尖锐湿疣,也可用5-Fu基底注射,多者可分批注射.

    2010-01-21 20:45:25 補充:

    ②噻替哌:主要用于5-Fu治疗失败的尿道内尖锐湿疣,每日用栓剂(每个含15mg),连用8天,也可将本品60mg加入10-15ml消毒水中,每周向尿道内滴注,保持半小时,副作用有尿道炎.亦可用本品10mg加入10ml浸泡患处,每日3次,每次半小时,治疗阴茎、龟头冠状沟湿疣,主要用于经其它方法治疗后,尚有残存疣体或复发者.也可将此溶液再稀释两倍浸泡局部,以预防复发.

    2010-01-21 20:45:47 補充:

    ③秋水仙碱:可用2-8%的生理盐水溶液外涂,涂两次,间隔72小时治疗阴茎湿疣,涂后可出现表浅糜烂.

    ④争光霉素或平阳霉素:用0.1%的生理盐水溶液作皮损内注射,每次总量限制在1毫升(1mg),大多一次可愈.平阳霉素为争光霉素换代品,用法基本相同,亦有用平阳霉素10mg溶于10%普鲁卡因20ml内注射.

    2010-01-30 11:30:41 補充:

    )5%5-Fu软膏 5-Fu是一种常用的抗肿瘤药物,它能抑制细胞的增殖,力量较为温和,一般需治疗2~3周。

    (2)优亭康:纯中药国准字,无痛苦,无副作用,去火清毒通过调节人体免疫系统功能,培养主动抗体,增强人体自身的抗病毒能力防复发效果较好

    (3)醋酸:三氯醋酸是一种强酸,可用来烧灼疣体,一般用于治疗Ⅱ型病变。涂抹前先用棉球醮2%的卡因贴敷于病变局部3 ̄5分钟后,用棉签醮50%三氯醋酸涂抹病变,使药液达基底部;

    (4)1-3%的肽丁胺霜 外搽本药,每日2次

    (5)20-25%的足叶草酯酊(或0.5%足叶草脂毒素液)或液体石蜡制剂,直接搽于皮损处。

    2010-01-30 11:31:55 補充:

    6/争光霉素、平阳霉素兑生理盐水,外涂患处,每周用药2~3次。

    无环鸟苷膏

    7/保持患处清洁干燥,用3%过氧化氢溶液或1:5000高锰酸钾溶液等清洗。

    8/1-5%氟尿嘧啶霜或2%氟尿嘧啶溶液外搽,每日1次,每次只搽几个病损,以免粘膜发生糜烂反应。

    9/1%酉丁胺膏涂控,一日三次,坚持6周亦可望治愈。

    (10)微波治疗。这是进入90年代后兴起的治疗方法。它的原理是利用微波的高频震动,使疣体内部水分蒸发,坏死脱落。但面恢复较慢,容易继发感染。所以微波治疗特别适用于治疗疣体较大的治疗注意有可能会影响男性的功能。

    2010-01-30 11:35:20 補充:

    Background.We performed a study to better characterize the natural history of genital human papillomavirus (HPV) infection in a cohort of closely followed adolescent women.

    2010-01-30 11:35:43 補充:

    Methods.A cohort of 60 adolescent women was followed over a 2.2-year period, on average. A median of 41.5 self-collected vaginal and clinician-obtained cervical swabs were obtained from each subject

    2010-01-30 11:36:12 補充:

    Conclusions.The cumulative prevalence of HPV infection in sexually active adolescent women is extremely high, involves numerous HPV types, and frequently results in cervical dysplasia.

    2010-01-30 11:36:49 補充:

    Results.HPV was detected in 45.3% of all adequate specimens, by use of a polymerase chain reaction/reverse blot strip assay. Oncogenic—or high-risk (HR)—HPV types were detected in 38.6% of specimens,

    2010-01-30 11:36:54 補充:

    and nononcogenic—or low-risk (LR)—types were detected in 19.6% of specimens. During the entire study period, 49 of 60 subjects tested positive for HPV (cumulative prevalence, 81.7%).

    2010-01-30 11:37:16 補充:

    The most frequently detected HR types were HPV types 52, 16, and 59. Infections with multiple HPV types were common. The median duration of persistence of a specific HPV type was 168 days,

    2010-01-30 11:37:35 補充:

    and HR types were more persistent than LR types. Abnormal cervical cytological results occurred in 37% of the adolescent women and were significantly associated with HR HPV infection.

    2010-01-30 11:38:34 補充:

    Cited byBertran Auvert, Pascale Lissouba, Ewalde Cutler, Kevin Zarca, Adrian Puren, Dirk Taljaard. (2010) Association of Oncogenic and Nononcogenic Human Papillomavirus With HIV Incidence. JAIDS Journal of Acquired Immune Deficiency Syndromes 53:1, 111-116

    Online publication date: 1-Feb-2010.

    2010-02-23 22:55:40 補充:

    Treatment:by cdc

    Visible genital warts can be removed by the patient him or herself with medications. They can also be treated by a health care provider. Some people choose not to treat warts, but to see if they disappear on their own. No one treatment is better than another.

    2010-02-23 22:56:06 補充:

    Abnormal cervical cells (found on a Pap test) often become normal over time, but they can sometimes turn into cancer. If they remain abnormal, these cells can usually be treated to prevent cervical cancer from developing.

    2010-03-31 23:08:04 補充:

    1注射牛痘病毒殺死癌細胞

    2改變生活習慣與飲食:早睡早起,

    少魚肉,多蔬果汁,避免糖類蛋白質與固體食物連續5~6周

    2010-05-01 11:21:35 補充:

    研究生 : 陳佳鈺

    校院名稱 : 臺北醫學大學

    固態栽培 樟芝防治癌症之重要機轉 - 癌症逆轉

    固態栽培 樟芝防治癌症之重要機轉 - 癌症逆轉

    根據研究發現癌症是可以逆轉的,以感染病毒或以化學物質處理或與放射線接觸等方式藉著啟動腫瘤細胞中之逆轉作用機制,讓癌細胞不表現腫瘤特性,甚至於恢復成相當程度之正常細胞。

    2010-05-01 11:23:36 補充:

    使用替代療法:運用生化科技產品抑制癌細胞增生

    2010-05-27 00:23:19 補充:

    所有癌症皆可治療,但能否根治與病換的生活習慣與環境,遺傳與飲食,

    都有極大的影響,現今治療癌症作有效的策略,

    當然是以中西醫合併治療最有效,

    除手術化寮與抗癌標靶藥物以外,

    還是可以運用輔助替代療法抗癌,

    從飲食免疫療法控制病情,

    補充大量維他命與促使癌細胞凋零的食物:綠茶素,草莓,大蒜,靈芝,

    香菇等食物對於抗癌,延長病患壽命有不錯的效果!

    Source(s): internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet, internet/webmed, internet/webmed, internet/webmed, internet/webmed, internet/webmed, internet/webmed
  • ,..
    Lv 7
    1 decade ago

    您好

    性病疣俗稱椰菜花。性病疣是經與病者性交傳染得來的,一般的潛伏期由一個月至八個月不等,平均則為三個月。患者在感染病毒後,性器官的皮膚或黏膜上 會出現呈長尖型或扁平的肉色小粒。小粒會逐漸增加 成簇,而且容易破損、流血和發炎。男性患者的受感 染部位多在陰莖的包皮系帶、陰莖冠溝,或尿道出口。 女性則多在陰道出口、陰唇、陰道及子宮頸。有肛交的男女,肉粒也有可能長在肛門或會陰 。

    加強免疫力吧!病毒是潛伏在人體免疫細胞內,到身體疲倦或免疫力差時便會發作。

    http://kgkg511.pixnet.net/blog/post/26590465

  • 菜花 ( 尖頭濕疣肉芽 )其病原體是 HPV 人類乳頭狀瘤病毒 : 單純性菜花肉芽,生於男女生殖器,生長出小粒肉芽,逐漸增多長大,其症不痛不癢,俗稱 : 菜花 ( 尖頭濕疣肉芽 ) 男性生於龜頭冠狀溝、陰莖、睪丸、肛門等處。

    女性生於陰部、陰唇陰道口內外、肛門內外、子宮內肌瘤等處。治療於電療雷射,冷凍開刀手術法,只能把表面肉芽去除,體內病毒不清除乾淨,不能徹底根治,且易再復發。所謂「斬草不除根、春風吹又生」。尤其是女性陰部或陰道菜花肉芽用電燒後,其病毒最易轉移子宮內,造成子宮肌瘤,如果嚴重惡化則成子宮癌,到最後把整個子宮去除拿掉。中醫藥內服用排毒殺菌,將體內病毒菌由大小便排出,外用消疣膏自然脫落,內服兼外用,徹底根本治療,治癒後不再復發。

    提供您參考資料 http://www.23710088.url.tw/html/02/index3.htm

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