What is the OD Dosage for Morphine?
just as the question suggest and i am not going to shoot morphine just curios as to what is the dosage
- 1 decade agoFavorite Answer
The lethal dose of morphine in humans varies widely depending on several factors, including age, health, whether other drugs are taken at the same time, whether the morphine is injected or taken orally, and, most importantly, whether the user has tolerance to morphine or other opioids.
It is generally assumed that the ORAL lethal dose of morphine (as the sulfate or hydrochloride salts) in a healthy adult who has NO TOLERANCE to opioids ranges from 120 mg to 250 mg. [See, e.g., MSDS for morphine at: http://www.paddocklabs.com/forms/msds/morpsulf.pdf... [See also toxicity information on Kadian (oral morphine):http://www.flexyx.com/K/Kadian.html.]
The lethal dose of IV, SC, or IM (INJECTED) morphine in a healthy adult WITH NO TOLERANCE is more difficult to gauge, but probably ranges between 1/6th to 1/3rd the oral dose, as oral morphine is only 1/3 to 1/6 the potency of PARENTERAL (INJECTED) morphine. This is due to the fact that oral morphine is poorly metabolized.
It is important to note that individuals with a TOLERANCE to opioids can take massive amounts of morphine without exhibiting toxicity, such that such an individual could take 10-20 times the lethal dose for a non-tolerant individual without any ill effects.
- LisaLv 44 years ago
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I am not a doctor or pharmacist... but I take the same dosage of Morphine for an injury I have.. and I believe the signs are shallow breathing...and short breaths. But, I think you are in the clear, becuase when you crush it, the danger zone is immediately after you snort. That is the whole idea of snorting, so that you get the big rush right away... So,now 4 hours later...the fact that you can type and form a question, is a good indication that you are going to be fine... No worries, I am no hypocrite, we ALL do stuff that is stupid, I have done this,(with a 120 mg total dosage) I dont judge you at all. Actually, I am envious, I bet it felt good! lol
- 4 years ago
Is point .48 mg/liter a fatal amount with point .12 ethanol?