白目毛 asked in 社會與文化語言 · 1 decade ago

幫我翻譯一段報告可以嗎...最好是藥學的

Loop diuretics block the sodium–potassium–chloride transporter, thiazide diuretics block the electroneutral sodium–chloride transporter, and amiloride and triamterene block apical sodium channels.

All diuretics except spironolactone reach these luminal transport sites through the tubular fluid; all but osmotic diuretics are actively secreted into the urine by proximal tubule cells.

A high degree of protein binding (>95 percent) limits glomerular filtration, even in patients with hypoalbuminemia.

In effect, binding to serum proteins traps the diuretic in the vascular space so that it can be delivered to secretory sites of proximal tubule cells.

Loop and thiazide diuretics and acetazolamide are secreted through the organic-acid pathway, and amiloride and triamterene through the organic-base pathway.

2 Answers

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  • 懿珩
    Lv 4
    1 decade ago
    Favorite Answer

    Loop diuretics block the sodium–potassium–chloride transporter, thiazide diuretics block the electroneutral sodium–chloride transporter, and amiloride and triamterene block apical sodium channels.

    作用於亨耳氏管的利尿劑主要機轉為阻斷納-鉀-氯離子的交換,thiazide類的利尿劑主要是阻斷鈉-氯離子電解中和的交換,amiloride 以及 triamterene 阻斷腎小管末端的納離子管道.

    All diuretics except spironolactone reach these luminal transport sites through the tubular fluid; all but osmotic diuretics are actively secreted into the urine by proximal tubule cells.

    所有的利尿劑除了spironolactone以外接經由腎小管旁微血管液進入腎小管內運輸系統,除了滲透性利尿劑外其他的都是經由近端腎小管細胞主動分泌排出至尿中.

    A high degree of protein binding (>95 percent) limits glomerular filtration, even in patients with hypoalbuminemia.

    他與蛋白質的高結合率(大於95%)減少了他在腎絲球的過濾,即使是低蛋白的病患亦然.

    In effect, binding to serum proteins traps the diuretic in the vascular space so that it can be delivered to secretory sites of proximal tubule cells.

    因此因為他與蛋白質的結合使這些利尿劑都被留在血液系統內而被運輸到腎小管近端排出.

    Loop and thiazide diuretics and acetazolamide are secreted through the organic-acid pathway, and amiloride and triamterene through the organic-base pathway

    亨耳氏管類及thiazide類的利尿劑以及acetazolamide都是經由有機-酸性管道排出,而amiloride以及triamterene則是經由有機-鹼性管道排出

  • 1 decade ago

    圈利尿藥塊鈉鉀氯化物運輸者, thiazide利尿藥塊electroneutral鈉氯化物運輸者和氨氯吡脒和triamterene塊頂端鈉渠道。 除了spironolactone伸手可及的距離的所有利尿藥這些照明運輸站點通过筒形流體; 几乎滲透的利尿藥有效地被藏匿入尿由接近小管細胞。 高度蛋白質捆綁(> 95%)限制glomerular濾清,甚而在有hypoalbuminemia的患者。 实际上,束縛對血清蛋白設陷井利尿在血管空間,以便它可以被交付到接近小管細胞分泌站點。 圈和thiazide利尿藥和acetazolamide通过有機酸路被藏匿和氨氯吡脒和triamterene通过有機基地路。

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