Yes, because it has a negative connotation, which originally stemmed from something very sexist.. but most of us don't get too offended, because if we do, "we are crazy feminists" and face even more scrutiny. Although, we do try to over compensate for our perceived shortcomings...it's sucks to be underestimated just because you have a vagina.
I imagine its the same for reaction for gay individuals, as their orientation has made it to the current vernacular as translating into something "stupid". It's pretty demeaning, although, it's so common that it looses a bit of its luster.
I really don't know if that's a good thing or a bad thing.