A portion of a specific DNA molecule consists of the following sequence of nucleotide triplets:?
A portion of a specific DNA molecule consists of the following sequence of nucleotide triplets:
TAC GAA CTT GGG TCC
a. what would be the correct amino acid sequence for this short polypeptide?
b. Describe the steps in the synthesis of this polypeptide?
c. what would be the effect of a deletion or an addition in one of the DNA nucleotides?
- 1 decade agoBest Answer
a.the mRNA would read GGA CCC AAG UUC GUA (the corresponding amino acids can be pulled from a chart)
b. the steps in peptide synthesis is transcription(dna->mrna) (if its eukaryotic then the mrna is to be processed to removed introns) then the mature mrna is translated by ribosome.
c. adding or deleting a nucleotide would cause a frame shift mutation. this where the nucleotides, are essentially shifted, in the above mrna sequence(a) if we were to remove the dna C then our mrna would be GAC CCA AGU UCG UA- this would give us an entirely different peptide.Source(s): biochemist/molecular biologist
- BeverlyLv 44 years ago
a) 1.- get the RNA sequence of each. 2.- get its anticodon. b) all the amino acids following the deleted or added nucleotide will change. c) the mutation can vary depending the location of the substitution; if it was the last nucleotide it can still make the same amino acid, but if it was the first it will entirely change the amino acid.
- Anonymous1 decade ago
b.) http://en.wikipedia.org/wiki/Protein_synthesis#Pro... - Transcription to translation