You didn't explain why you need the mortgage modification, so I am going to make the assumption that you can't afford the monthly payment and therefore are hoping to do a modification to lower the payment. Most lenders will deny you if you call their customer service dept, however there are some very good loan modification company's that will represent you and they deal with the loss mitigation department and if you can prove a hardship and the reason why it has become so difficult to pay your mortgage, then they will work with you even if you're not late on your mortgage yet. But you need that professional representation - similar to the situation that you wouldn't go to court on your own. You only have one chance to get a really good aggressive modification and you want to show the lender why it is in their best interest to do the modification and keep you in the house.
The rate on the 1st isn't extremely high, but they could potentially modify it and the second mortgage could absolutely be lowered. In addition, if you owe more on your house that it is currently worth, they will do a principal reduction as well.
So you do have options, you just need to seek out the legitimate loan modification company's...but be careful because they are popping up on every corner now...since loan modification is the next greatest trend.
Hope this helps. Best of luck to you.