超急...英文翻譯中文!!!

1 Introduction

Since there is an increase in the elderly population,

occlusal reconstruction is of importance from the point of

view of the quality of life of patients. In order to accomplish

this using dental implants, osseointegration should be

completed promptly, and once completed, it should be

maintained for as long as possible. Also, it is very important

for patients to achieve mature bone of high integrity as

soon as possible after treatment. In fact, however, it often

takes a long time to achieve bone which is identical to

existing bone in its properties. In order to obtain functional

bone as soon as possible, it is critical to enhance both the

proliferation and differentiation of osteogenic cells. Basic

fibroblast growth factor-2 (FGF-2) is well known to facilitate

the proliferation of osteoblasts in vitro and bone repair

in vivo [1–4]. On the other hand, melatonin, a hormone

that is secreted by the pineal gland during the night and

controls circadian rhythms, was recently reported to promote

the differentiation of osteoblasts in vitro and bone

formation in vivo [5–9]. From these facts, we focused on

the possibility that FGF-2 and melatonin synergistically

promote bone formation in vivo by enhancing both the

proliferation and differentiation of osteogenic cells. The

aim of the present study was to evaluate the effect of FGF-

2 and melatonin on osseointegration around titanium

implants.

2 Answers

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  • 1 decade ago
    Favorite Answer

    1介紹因为有在年長人口的增量,咬合重建是重要從生活水平患者角度看。 使用牙插入物,為了完成此, osseointegration應該 完成及時地和一次完成,它應該是維護為越久越好。 并且,儘快達到成熟骨頭高度誠實在治療以後患者是非常重要的。 实际上,然而,經常需要很长时间達到是相同的骨頭在它的物產的現有的骨頭。 為了儘快得到功能骨頭,提高成骨性的細胞的擴散和分化是重要的。 基本的成纖維細胞成長因素2 (FGF-2)是知名的促進osteoblasts體外和骨頭修理的擴散體內[1-4]。 在另一隻手上, melatonin,由松果体和控制昼夜生理节律夜間藏匿的激素,最近報告促進osteoblasts體外和骨頭的分化體內形成[5-9]。 從這些事實,我們集中于可能性FGF-2和melatonin通过提高兩協同作用地促進骨頭形成體內成骨性的細胞的擴散和分化。 本研究的目標将評估FGF- 2和melatonin的作用对osseointegration在鈦附近植入管。

    Source(s): 字典
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  • 1 decade ago

    1個人介紹

    自從有老人口的增加,

    occlusal 重建具有來自點的重要

    病患的生活質量的意見。 為了完成

    這使用的鑲牙,osseointegration 應該是

    迅速完成,並且曾經完成,它應該

    為儘可能長保持。 此外,它非常重要

    病患取得高的完整的成熟的骨頭作為

    不久作為可能的在處理之后。 實際上,不過,經常的它

    需要很長時間取得骨頭,這與相同

    在它的特性裡的現有的骨頭。 為了獲得職能

    盡快骨頭,關鍵都提升

    osteogenic小屋的發展和區別。 基本

    fibroblast增長系數-2(FGF-2)為清楚地了解簡化

    在試管內的osteoblasts的發展和骨骼修復

    在活體內 [1 V4 ]. 另一方面,melatonin,激素

    在夜晚松果體腺分泌那和

    控制晝夜節律,最近被報告發起

    在試管內區別osteoblasts和骨頭

    在活體內形成 [5 V9 ]. 從這些事實中,我們集中于

    可能性那配合的FGF-2和melatonin

    提升骨頭形成在活體內以提升都

    osteogenic小屋的發展和區別。

    目前的研究的目的將評價FGF的影響

    在鈦周遭的在osseointegration上的2和melatonin

    種植。

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