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cat asked in 社會與文化語言 · 1 decade ago

醫學期刊翻譯高手請進

可不可以幫我翻譯.....醫學期刊...急用中

Spuriously high phosphate level which is promptly resolved after plasmapheresis in a patient with multiple myeloma

Abstract

We present a 57 year old female patient with IgG multiple myeloma and marked hyperphosphatemia . The patient had no clinical symptoms related to hyPerphosphatemia . Serum inorganic phosphate measurements were repeated on sulfosal - icylic acid deproteinized serum samples , yielding normal phosphate levels . We realized that this hyPerphosphatemia was spurious because of high paraprotein levels . Afterwards , therapeutic plasma exchange ( TPE ) was administered due to hyPerviscosity and bleeding tendency . After the administration of TPE , serum phosphate was redueed to normal level . Therapeutic plasma exchange resulted in steady -state serum phosphate levels during the three months follow up period .

We concluded that high phosphate levels must be confirmed by measuring in deproteinized serum samples in multiple myeloma patients in order to distinguish pseudohyPerphosphatemia from the true ones . In addition , TPE effectively reduces the spuriously elevated phosphate levels possibly by removing paraproteins .

2 Answers

Rating
  • tammy
    Lv 5
    1 decade ago
    Favorite Answer

    出現假性燐酸鹽量過高的多發性骨髓瘤患者,在經過血漿減除術後可以迅速的得到改善。

    摘要

    我們將呈現一位57歲的女性患者,她患有 IgG 抗體的多發性骨髓瘤以及明顯的血內燐酸鹽過多。這位患者並沒有血內燐酸鹽過多症的臨床症狀。血漿中無機燐酸鹽檢測是使用重複的磺基水楊酸去蛋白處理,所產生的正常燐酸鹽量的血漿檢體。我們發覺到由於血中副蛋白量過高所引發的血內燐酸鹽過多是屬於一種假象。然後,由於血液濃度過高和血液流動趨勢而給予治療性血漿置換術(TPE)的治療。經過治療性血漿置換術(TPE)的治療後,血漿中的燐酸鹽減低到正常量。治療性血漿置換術(TPE)的治療效果,經過三個月的追蹤期後,顯示對血漿中燐酸鹽量的穩定有效果。

    我們獲得結論,高血中燐酸鹽量必須是檢測經過去蛋白血清處理的血漿檢體,而此種血漿檢體則是多發性骨髓瘤患者中已排除是血內燐酸鹽過多症的假性血內燐酸鹽過多症患者所收集採得。加上,治療性血漿置換術(TPE)有效降低假性的燐酸鹽量過高的原因,可能是因為去除了副蛋白的緣故。

  • 1 decade ago

    敏捷地被解決之後血漿除去法在病人和多重的偽造地高的磷酸鹽水平面骨髓瘤

    難解

    我們出席的57歲女性病人和免疫球蛋白多發性骨髓瘤和標記hyperphosphatemia . 病人有沒有臨床徵狀關係於hyPerphosphatemia . 漿液無機磷酸鹽測定法被重複上sulfosal - icylic諷刺的deproteinized漿液採樣 , 被迫放棄正磷酸鹽標準 . 我們認識到這hyPerphosphatemia是偽造的由於高的異常蛋白水平面的 . 其後 , 治療的血漿交換 ( TPE ) 被管理由於粘性過大和流血傾向 . 之後管理的TPE , 漿液磷酸鹽是redueed到正常水位 . 治療的血漿交換結果是穩固的 -時期情形漿液磷酸鹽標準的時間3個月追究 .

    我們推斷那個高的磷酸鹽標準必定得被證實以測量的在脫蛋白質漿液採樣在多發性骨髓瘤病人為了辨認pseudohyPerphosphatemia從真理一 . 此外 , TPE有效地減低偽造地升高的磷酸鹽標準可能地附近移動異常蛋白 .

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