How does having larger than normal red blood cells affect a person?

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Significant Megaloblastosis (very high MCV on CBC) is almost always a correctable deficiency of Vitamin B12 or folate. If the Mean Corpuscular Volume (MCV value on the CBC report) is only slightly elevated, it may be a normal variant for you and have no negative health implications.
If you have a megaloblastic anemia, it needs to be appropriately diagnosed and treated.


MD hematologist/oncologist
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  • hanora answered 6 years ago
    It might be a sign of a B vitamin deficiency. But there are people who have this and it is just normal for them and has no effect on their health.
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  • jlevilgenious answered 6 years ago
    i don't know exactly but i think it would be that there would be less room for the cells to be able to travel in and it would be harder to pump them throughout the body. this means less oxygen. though, like i said, I'm not a doctor and this is just speculation.
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