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Anonymous
Anonymous asked in 科學其他:科學 · 1 decade ago

細胞病變效應(CPE)和細胞毒殺效應(CTE)的定義~急需

我想請問細胞病變效應(CPE)和細胞毒殺效應(CTE)的定義和解釋

越詳細越好,因為報告急用,希望一天內有答案,給20點~~

2 Answers

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  • YCP
    Lv 5
    1 decade ago
    Favorite Answer

    Cytopathic effect

    refers to degenerative changes in cells (especially in tissue culture) associated with the multiplication of certain viruses. When in tissue culture, the spread of virus is restricted by an overlay of agar (or other suitable substance) and thus the cytopathic effect may lead to formation of plaque. Thus identification of a viral infection can be made by examining the characteristic cytopathic effect produced on different cell sheets. This method however is relatively slow and not all viruses will grow on cell sheets.

    Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are a chemical substance or an immune cell.

    Cytotoxicity can be measured by the MTT assay, Trypan blue (TB) assay, Sulforhodamine B (SRB) assay, WST assay and clonogenic assay.

    Antibody-dependent cell-mediated cytotoxicity (ADCC) describes the cell-killing ability of certain lymphocytes, which requires the target cell being marked by an antibody. Lymphocyte-mediated cytotoxicity, on the other hand, does not have to be mediated by antibodies; nor does complement-dependent cytotoxicity (CDC), which is mediated by the complement system.

    Three groups of cytotoxic lymphocytes are distinguished:

    Cytotoxic T cells

    Natural Killer cells

    Natural Killer T cells

    Source(s): 維基
  • Anonymous
    1 decade ago

    作業自己作..../ \

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