whats the difference between Hodgkin Lymphoma and non Hodgkin Lymphoma?
- 1 decade agoFavorite Answer
Hodgkin lymphoma was named for Thomas Hodgkin, an English physician who described several cases of the disease in 1832.
Lymphoma is a general term for a group of cancers that originate in the lymphatic system. The prefix "lymph-" indicates their origin in the malignant change of a lymphocyte and the suffix "-oma" is derived from the Greek suffix denoting "tumor." The usual presentation is enlarged lymph nodes found on either or both sides the neck, axillae, and the groins. Some lymph nodes can also be found in the mediastinum (thorax) and abdomen.
Both Hodgkin's disease and non-Hodgkin's lymphoma are lymphomas, a type of cancer that originates in a subset of white blood cells called lymphocytes — an important component of your immune system. The main difference is in the specific lymphocyte each involves.
A doctor can tell the difference between Hodgkin's and non-Hodgkin's by examining the cancer cells under a microscope. If in examining the cells, the doctor detects the presence of a specific type of abnormal cell called a Reed-Sternberg cell, the lymphoma is classified as Hodgkin's. If the Reed-Sternberg cell is not present, the lymphoma is classified as non-Hodgkin's.
The distinction is important because the treatment for each type can be very different.Source(s): I'm a hematologist. http://www.mayoclinic.com/health/lymphoma/AN01209 http://www.cancerbackup.org.uk/QAs/LymphomaHodgkin... http://www.cancernorth.nhs.uk/ncn/Site/cancertypes... http://www.patientinfo.selcn.nhs.uk/cancertypes/No...
- Anonymous4 years ago
hi, Lymphoma has 2 important varieties – Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma. Hodgkin’s lymphoma / Hodgkin’s ailment (HD) – is a maximum cancers of a undeniable form of lymphatic cellular, the Reed-Sternberg cellular that's a extensive strange white blood cellular. whilst this cellular is detected in a pattern from the lymph node, the prognosis for Hodgkin’s ailment is shown. It happens in youthful human beings and youthful adults and is outstanding from the different sort of lymphomas in basic terms by utilizing the presence of the strange cellular. This ailment is the extra curable form out of all lymphomas. Non-Hodgkin’s lymphoma (NHL) – often called lymphosarcoma, that's a ailment that originates in one form of lymph tissue – the two in the lymph nodes, spleen, bone marrow or any of the different tissues. In NHL, a undeniable form of white blood cellular is affected. those would desire to be the cells that make protecting proteins, or people who've organic killing properties. The ailment is assessed on the inspiration of how briskly it grows. Very quickly growing to be NHL is seen severe-grade at the same time as the sluggish growing to be form is assessed as low-grade. the indicators are: the two the forms of lymphomas have some undemanding indicators: Enlarged yet painless lymph nodes Fatigue weight alleviation Unexplained fevers Sweating at night some indicators extra undemanding in HD are enlarged liver and spleen, chest soreness with the aid of blockage in the blood vessels, subject in respiratory and dermis rashes. different indicators extra undemanding in NHL are indicators of anaemia, tendency to bruise and bleed surely, soreness in the bones and better threat of infections. The prognosis Lymphoma is clinically determined by utilizing biopsies the place a tissue pattern is examined for abnormalities. If the presence of the Reed-Sternberg cellular is detected, HD is shown. the countless biopsies that are carried out are from the bone marrow, lymph nodes and the cancerous mass of cells. as properly, blood assessments which comprise CBC (finished blood count form) are carried out. X-rays of the suspected section are studied. with the aid of fact the ailment spreads in tiers, shifting from one lymph node to a lymphatic tissue and ultimately to the completed physique, CT scans of the affected section are taken.
- 1 decade ago
The simplest difference is the type of white blood cell that is malignant. While it is possible that they may look alike under the microscope, the appearance of the malignant lymph nodes are noticeably different and the laboratory characteristics of the malignant cells are mightily different.
Second, the symptoms and the way the tumor can spread are quite different. Lastly, the treatments are different.
If you could be more specific in what you need, you might get more assistance.
Of course, reading about this on the internet may answer your questions, too.Source(s): I'm an oncologist