Down Syndrome???

My grandmothers cousin has down syndrome will my kids have it???He is the only family member on both sides that we know of having it.

6 Answers

  • 1 decade ago
    Best Answer

    Dear Buck Master


    Down syndrome is the most common cause of mental retardation and malformation in a newborn. It occurs because of the presence of an extra chromosome.


    Chromosomes are the units of genetic information that exist within every cell of the body. Twenty-three distinctive pairs, or 46 total chromosomes, are located within the nucleus (central structure) of each cell. When a baby is conceived by the combining of one sperm cell with one egg cell, the baby receives 23 chromosomes from each parent, for a total of 46 chromosomes. Sometimes, an accident in the production of a sperm or egg cell causes that cell to contain 24 chromosomes. This event is referred to as nondisjunction. When this defective cell is involved in the conception of a baby, that baby will have a total of 47 chromosomes. The extra chromosome in Down syndrome is labeled number 21. For this reason, the existence of three such chromosomes is sometimes referred to as Trisomy 21.

    In a very rare number of Down syndrome cases (about 1–2%), the original egg and sperm cells are completely normal. The problem occurs sometime shortly after fertilization; during the phase where cells are dividing rapidly. One cell divides abnormally, creating a line of cells with an extra chromosome 21. This form of genetic disorder is called a mosaic. The individual with this type of Down syndrome has two types of cells: those with 46 chromosomes (the normal number), and those with 47 chromosomes (as occurs in Down syndrome). Some researchers have suggested that individuals with this type of mosaic form of Down syndrome have less severe signs and symptoms of the disorder.

    Another relatively rare genetic accident which can cause Down syndrome is called translocation. During cell division, the number 21 chromosome somehow breaks. A piece of the 21 chromosome then becomes attached to another chromosome. Each cell still has 46 chromosomes, but the extra piece of chromosome 21 results in the signs and symptoms of Down syndrome. Translocations occur in about 3–4% of cases of Down syndrome.

    Down syndrome occurs in about one in every 800–1,000 births. It affects an equal number of boys and girls. Less than 25% of Down syndrome cases occur due to an extra chromosome in the sperm cell. The majority of cases of Down syndrome occur due to an extra chromosome 21 within the egg cell supplied by the mother (nondisjunction). As a woman's age (maternal age) increases, the risk of having a Down syndrome baby increases significantly. For example, at younger ages, the risk is about one in 4,000. By the time the woman is age 35, the risk increases to one in 400; by age 40 the risk increases to one in 110; and by age 45 the risk becomes one in 35. There is no increased risk of either mosaicism or translocation with increased maternal age.

    So….there are still possibility that you will have children with Down Syndrome.

    But I hope God will give you an healthy children

    Good luck.


    Anasthasia Pride

  • Ashley
    Lv 4
    1 decade ago

    Down Syndrome has no genetic links. If you're under 30, you have a chance in about 1 in 800 of having a child with Down Syndrome.

    Source(s): work in state office of MR
  • 1 decade ago

    If your really worried about it get genetic counseling. They will go over your family tree and do some blood work and let you know better what the chances are. But just so you know there are a lot of reasons besides genetics for Down Syndrome. Good luck.

  • konen
    Lv 4
    3 years ago

    it incredibly is spelled down syndrome. regrettably that's incorrect. The difficulty replaced into got here across by using johnathan down and named after him so it belongs to him giving the syndrome the appostrafy s. So it will be Down's Syndrome yet all medical textual content cloth will spell it without the s.

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  • 1 decade ago

    down syndrome is a genetic anomaly that randomly occurs. the most common type of ds is trisomy 21 (90% of people with ds have this form) then there is mosaics and only about 5% have this form so it is kind of rare and these two types of ds are not hereditary. however, there is one form of ds that ishereditary, it is called translocation and is even rarer still.I can not tell you if any of your children would have down syndrome...I am not a geneticist...nor do I have a working "chrystal ball" I am just a mom to a little boy who happens to have down syndrome and I have read a lot about it since finding out my son has ds.....

  • Anonymous
    1 decade ago

    Probably not-it is not passed on through generations(except possibly by teh perosn with down syndrome)

    It is a genetic mutation-teh gene starts out right, but then breaks-(doubles) or fails to separate-and instead of each parent givnig one gene-one parent gives 2 genes...for a total of 3

    its not like cyctic fibrosis that is passed down parenst taht carry the egene

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