There is no BEST pain relief medication. Each patient has a need for the medication which best meets the needs of their condition, level of pain, and other related medical conditions. For many with an ACL injury, management with a Non-steriodal anti-inflammatory agent such as ibuprofen (MOTRIN) naproxen (Aleve) or a COX-2 such as celecoxib (Celebrex) control the discomfort and increases function. For others, their condition or pain tolerance requires a stronger medication such as tramadol or even hydrocodone. These last 2, however are both opioid medications and may be habit forming, therefore, they are usually preferred for use in patients in the immediate pre and postoperative periods.
If surgery has been recommended, the physician should recommend appropriate medication, if it does not control the pain, contact your physician and ask for something stronger.
I will tell you that when people approach a physician with a particular medication in mind, they are often thought of as "drug seeking", even when they are earnestly trying to manage their pain. Discuss the pain with your physician and let them prescribe an appropriate medication.
Pain Management/Headache Specialist