KK
Lv 4
KK asked in 健康疾病與處置癌症 · 1 decade ago

幫我翻譯子宮內膜癌文章

請各各懂 醫療.生化類 英文文獻 的高手雲集

請進 這裡需要您的幫助 拜託

幫我翻譯有關生化的文章

Endometrial carcinoma is a low grade curable malignancy and most patients present with early disease with excellent survival. Of all female pelvic malignancies, it seems to have more advocates for different treatment plans than any other. The incidence rises with age and is significantly increased when there is exposure to unopposed estrogen. The long term use of tamoxifen for breast cancer is also associated with an increased incidence of endometrial cancer. Transvaginal ultrasound and pipelle or hysteroscopy endometrial biopsies are tending to replace the traditional dilation and curettage in establishing a diagnosis. 90% of endometrial tumors are surgically resectable on presentation. This remains the first line management-minimally, a total extrafascial hysterectomy and bi-lateral salpingo oophorectomy. Prognostic factors include the histological grade, the depth of invasion of the myometrium, the presence or absence of lymph-vascular space invasion and involved regional nodes, tumor volume, and the presence or absence of involvement of the cervix.

Update:

還有下面這一段 總共兩段 都要翻完整 註明清楚 才給20點

Update 2:

The pelvis is a major anatomical site at risk of recurrence, and since cytotoxic chemotherapy and hormone therapies have limited effectiveness, radiotherapy is the adjuvant therapy of choice where adverse prognostic factors are present.

Update 3:

Pelvic lymhadenectomy is performed in most centers on therapeutic and prognostic grounds and to individualize adjuvant treatment. Treatment planning is conservative in order to reduce patients morbidity and overtreatment while maintaining acceptable recurrence and survival rates.

Update 4:

Patients who are not medically fit for surgery or who have inoperable disease are managed with radical radiotherapy but the results in both these groups are inferior to those obtained with radical surgery.

Update 5:

Spread outside the pelvis to para-aortic nodes may still be salvaged with local irradiation, but systemic disease is incurable and treatment is largely palliative including consideration of local irradiation, hormone therapy or chemotherapy for symptomatic relief.

Update 6:

上面這四小段都要翻

2 Answers

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  • 海海
    Lv 6
    1 decade ago
    Favorite Answer

    子宮內膜癌是一種低等級可治癒的惡性腫瘤,而且大部份的病人會出現早期症狀拌隨很好的存活率。在所有的女性的各種骨盆腔惡性腫瘤中,與其他惡性腫瘤比較,子宮內膜癌似乎有比較多的不同治療計劃的倡導者。子宮內膜癌致病率因年紀老化而提昇,而且暴露在無抗性的雌激素時,致病率更明顯增加。乳癌患者的子宮癌致病率增加與長期服用他莫昔芬 (tamoxifen)有關連。在建立診斷分析方面,經陰道的超音波和移液管(pipelle?pipette!)或子宮內膜活組織切片的子宮鏡檢查,已傾向取代傳統的擴張與刮除術。在文獻發表上,百分之九十的子宮腫瘤是以外科手術切除。這維持著最低階的管理,簡單的全部子宮切除法與雙側卵巢輸卵管切除術。預後的因子包括組織學等級,肌層組織侵入的深度,淋巴管空間被侵襲與區域性腫瘤的有無,腫瘤體積,和子宮頸被侵犯的有無。子宮頸是評估再發率風險的主要位置,而且自從細胞毒素的化學療法與荷爾蒙療法的有效性受到限制以後,當有害的預後因子存在時,會選擇放射線療法作為治療佐藥。為了治療和預後的理由,大部份的中心以個別化佐藥治療方式,執行骨盆腔lymhadenectomy。為了減少病患的罹病率與過度治療,而且要維持可接受的復病與存活比率,所以治療計劃是保守的。不適應醫學的外科手術或因惡疾正接受放射性射線治療處理的病人,他們的預後結果是劣於那些作放射性外科手術的病人。擴散到骨盆腔外面大動脈旁的結節仍然可以以局部放射拯救,但是系統的疾病可以治癒與否和包括局部放射,荷爾蒙治療的考慮或為了消除症狀的化療等的治療一直是廣汎的被辯論著。

  • 1 decade ago

    Endometrial 癌是一份低年級可醫治的敵意和多數患者當前以早期疾病以優秀生存。所有女性骨盆敵意, 它似乎有更多提倡者為不同的治療計劃比些其他。發生上升以年齡和顯著被增加當有對不受反對的女性荷爾蒙的暴露。長期用途tamoxifen 為乳腺癌並且同endometrial 癌症聯繫在一起的增加的發生。Transvaginal 超聲波和pipelle 或hysteroscopy endometrial 切片檢查法傾向於替換傳統擴張和刮術在建立診斷。90% endometrial 腫瘤外科地是resectable 在介紹。這保留第一線管理最小、總extrafascial 子宮切除和雙邊salpingo 卵巢切除術。預斷因素包括組織學成績、myometrium 的入侵的深度, 出現或缺乏淋巴血管空間入侵和被介入的地方結, 腫瘤容量、和出現或缺乏子宮頸的介入。

    Source(s): 從書名上找到的
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