If you like good party games and enjoy Cranium and Apples to Apples, you might try Cranium Hoopla - a cooperative game played by everyone racing against the timer, getting the other players to guess cards with drawing, charades style acting, and word clues.
Another fun, and funny party game is GiftTrap, which is all about figuring out which of some imaginary (and often rather wacky) gifts to give. (Warning: A few cards in the game are a bit risque; a little pocket is included to place such cards in out of the game if you are playing with people where such cards would be out of place).
For games with a little more strategy, you might look at:
Zooloretto - this clever game is themed around building a zoo. Each round, you can take one of the trucks carrying animals available, or add a new animal - but you have to be careful, since everyone else will get a chance to take the truck before you get another turn. It takes cleverness and planning to get the best filled zoo.
Ticket To Ride - a quick playing game where you try to collect sets of cards to place train routes across the country, trying to connect lots of destinations.
Might not be for everyone, but the game Ca$h N' Gun$ is good for some laughs; its a game of bluffing and threats as you use cards - and more importantly, foam guns - to "negotiate" over money (you're all bank robbers who can't agree on how to split it).
There's tons of good games out there!
www.boardgamegeek.com - everything about board games!
www.timewellspent.org - a great place to order games online; sadly, they will be closed for over month starting March 19th, so order quickly!