Will taking beer out of your refrigerator skunk it?

I came to visit some friends and bought a whole bunch of beer. When it was time for me to leave I wanted to take the beer with me. All my friends said that if I take it home it would skunk the beer, and totally ruin it. I live about eight hours away. I have never heard of this, but they could be right I guess.
Update: By skunk I mean- smells and tastes bad.
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